Presentation on the FK506 binding protein (FKBP) 51 as central molecular player in melanoma progression, because of its role in the positively regulation of cancer stemness, epithelial to mesenchimal transition genetic program and NF-κB-induced chemo and radio-resistance. Moreover, the talk was also focused on preliminary data showing that the spliced isoform of FKBP51, FKBP51s, is an immune signature of melanoma patients, virtually associated with tumor-induced immune tolerance and able to monitoring melanoma patient subjected to immune-therapy.
FKBP51 isoforms in cancer / Romano, Simona. - (2016). (Intervento presentato al convegno FKBP51 in health and disease Meeting tenutosi a University College London (UCL), London nel 20th October 2016).
FKBP51 isoforms in cancer
ROMANO SIMONA
2016
Abstract
Presentation on the FK506 binding protein (FKBP) 51 as central molecular player in melanoma progression, because of its role in the positively regulation of cancer stemness, epithelial to mesenchimal transition genetic program and NF-κB-induced chemo and radio-resistance. Moreover, the talk was also focused on preliminary data showing that the spliced isoform of FKBP51, FKBP51s, is an immune signature of melanoma patients, virtually associated with tumor-induced immune tolerance and able to monitoring melanoma patient subjected to immune-therapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
