A novel synthetic strategy for obtainment of (±)-3-deoxyradicinin (2) is reported. This synthetic methodology is more efficient than those previously reported in the literature and also shows higher versatility towards the introduction of different side-chains at both C-7 and C-2. The obtained compound (±)-2 shows phytotoxicity against the grass-weed buffelgrass comparable to that of the natural phytotoxin radicinin (1). Therefore, (±)-2 can constitute a more practical synthetic alternative to 1 as bioherbicide for buffelgrass control.
Synthesis and Herbicidal Activity against Buffelgrass (Cenchrus ciliaris) of (±)-3-deoxyradicinin / Marsico, G., Ciccone, M.S., Masi, M., Freda, F., Cristofaro, M., Evidente, A., Superchi, S., Scafato, P.. - In: MOLECULES. - ISSN 1420-3049. - 24:17(2019), p. 3193. [10.3390/molecules24173193]
Synthesis and Herbicidal Activity against Buffelgrass (Cenchrus ciliaris) of (±)-3-deoxyradicinin
Masi M.Writing – Review & Editing
;Evidente A.Writing – Review & Editing
;Superchi S.
;
2019
Abstract
A novel synthetic strategy for obtainment of (±)-3-deoxyradicinin (2) is reported. This synthetic methodology is more efficient than those previously reported in the literature and also shows higher versatility towards the introduction of different side-chains at both C-7 and C-2. The obtained compound (±)-2 shows phytotoxicity against the grass-weed buffelgrass comparable to that of the natural phytotoxin radicinin (1). Therefore, (±)-2 can constitute a more practical synthetic alternative to 1 as bioherbicide for buffelgrass control.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
