Psoriatic arthritis is a chronic inflammatory condition in which unbalanced inflammatory pathways act as key drivers of a wide range of articular and extraarticular manifestations. It is associated with a high prevalence of cardiovascular (CV) disease and risk factors. The precise pathogenetic mechanism of CV involvement has still to be clarified, but certain inflammatory cytokines play a key role in the atherosclerotic process. Studies have shown the potentially beneficial role of disease-modifying antirheumatic drug–induced immunosuppression and also anti–tumor necrosis factor drugs on CV diseases.
Cardiovascular Involvement in Psoriatic Arthritis / Atzeni, F.; Caso, F.; Masala, I. F.; Sarzi-puttini, P.. - 14:(2017), pp. 409-426. [10.1016/B978-0-12-803997-7.00016-8]
Cardiovascular Involvement in Psoriatic Arthritis
Caso, F.;
2017
Abstract
Psoriatic arthritis is a chronic inflammatory condition in which unbalanced inflammatory pathways act as key drivers of a wide range of articular and extraarticular manifestations. It is associated with a high prevalence of cardiovascular (CV) disease and risk factors. The precise pathogenetic mechanism of CV involvement has still to be clarified, but certain inflammatory cytokines play a key role in the atherosclerotic process. Studies have shown the potentially beneficial role of disease-modifying antirheumatic drug–induced immunosuppression and also anti–tumor necrosis factor drugs on CV diseases.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
