During the past years, a number of studies have demonstrated the positive effect of apple on ageing and different diseases such as cancer, degenerative and cardiovascular diseases. The unicellular yeast Saccharomyces cerevisiae represents a simple eukaryotic model to study the effects of different compounds on lifespan. We previously demonstrated that apple extracts have anti-ageing effects in this organism because of their antioxidant properties. In particular, the effect is related to the presence in this fruit of polyphenols, which give a large contribution to the antioxidant activity of apples.
Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells / Stirpe, Mariarita; Palermo, Vanessa; Bianchi, Michele Maria; Silvestri, Romano; Falcone, Claudio; Tenore, GIAN CARLO; Novellino, Ettore; Mazzoni, Cristina. - In: BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE. - ISSN 1472-6882. - 17:1(2017), p. 200. [10.1186/s12906-017-1666-7]
Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells
TENORE, GIAN CARLO;NOVELLINO, ETTORE;
2017
Abstract
During the past years, a number of studies have demonstrated the positive effect of apple on ageing and different diseases such as cancer, degenerative and cardiovascular diseases. The unicellular yeast Saccharomyces cerevisiae represents a simple eukaryotic model to study the effects of different compounds on lifespan. We previously demonstrated that apple extracts have anti-ageing effects in this organism because of their antioxidant properties. In particular, the effect is related to the presence in this fruit of polyphenols, which give a large contribution to the antioxidant activity of apples.File | Dimensione | Formato | |
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