The review deals with the application of the NMR advanced Mosher's method for the assignment of the absolute configuration to plant and fungal metabolites belonging to different classes of natural compounds. The structural and stereochemical characterization of these naturally occurring metabolites, as well as their biological properties as possible drugs or agrochemicals is reviewed. The importance of the absolute and relative stereochemistry on their biological properties is also highlighted. Successes and failures of application of the advanced Mosher's method are reported.

Application of Mosher's method for absolute configuration assignment to bioactive plants and fungi metabolites / Cimmino, Alessio; Masi, Marco; Evidente, Marco; Superchi, Stefano; Evidente, Antonio. - In: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. - ISSN 0731-7085. - 144:(2017), pp. 59-89. [10.1016/j.jpba.2017.02.037]

Application of Mosher's method for absolute configuration assignment to bioactive plants and fungi metabolites

CIMMINO, ALESSIO
Writing – Review & Editing
;
MASI, MARCO
Membro del Collaboration Group
;
EVIDENTE, ANTONIO
Supervision
2017

Abstract

The review deals with the application of the NMR advanced Mosher's method for the assignment of the absolute configuration to plant and fungal metabolites belonging to different classes of natural compounds. The structural and stereochemical characterization of these naturally occurring metabolites, as well as their biological properties as possible drugs or agrochemicals is reviewed. The importance of the absolute and relative stereochemistry on their biological properties is also highlighted. Successes and failures of application of the advanced Mosher's method are reported.
2017
Application of Mosher's method for absolute configuration assignment to bioactive plants and fungi metabolites / Cimmino, Alessio; Masi, Marco; Evidente, Marco; Superchi, Stefano; Evidente, Antonio. - In: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. - ISSN 0731-7085. - 144:(2017), pp. 59-89. [10.1016/j.jpba.2017.02.037]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/671747
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