As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences of mutations and epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm of these tumors. This chapter recapitulates the best known examples of molecular interactions potentially targetable to achieve these therapeutic evolutionary changes, to allow a better control of PC which, in 2012 alone, has still killed more than 28,000 men, in USA (Siegel et al, CA Cancer J Clin, 62:10-29, 2012; El-Amm, Aragon-Ching, Ther Adv Med Oncol, 5(1):25-40, 2013)

Crossroads of signaling pathways / Staibano, Stefania. - (2013), pp. 143-157. [10.1007/978-94-007-7149-9_8]

Crossroads of signaling pathways

STAIBANO, STEFANIA
2013

Abstract

As studies on PC progression continue to uncover a growing number of crosstalks and co-occurrences of mutations and epigenetic alterations, new drugs are getting approved bringing significant changes in the treatment paradigm of these tumors. This chapter recapitulates the best known examples of molecular interactions potentially targetable to achieve these therapeutic evolutionary changes, to allow a better control of PC which, in 2012 alone, has still killed more than 28,000 men, in USA (Siegel et al, CA Cancer J Clin, 62:10-29, 2012; El-Amm, Aragon-Ching, Ther Adv Med Oncol, 5(1):25-40, 2013)
2013
9789400771499
9789400771499
Crossroads of signaling pathways / Staibano, Stefania. - (2013), pp. 143-157. [10.1007/978-94-007-7149-9_8]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/643574
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact