Through a transcriptome microarray analysis, we have isolated Anterior gradient protein 2 (AGR2) as a gene up-regulated in papillary thyroid carcinoma (PTC). AGR2 is a disulfide isomerase over-expressed in several human carcinomas and recently linked to endoplasmic reticulum (ER) stress. Here, we analyzed the expression of AGR2 in PTC and its functional role.

Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells / DI MARO, Gennaro; Salerno, Paolo; Unger, Kristian; Orlandella, FRANCESCA MARIA; Monaco, Mario; Chiappetta, Gennaro; Thomas, Gerry; Oczko Wojciechowska, Malgorzata; Masullo, Mariorosario; Jarzab, Barbara; Santoro, Massimo; Salvatore, Giuliana. - In: MOLECULAR CANCER. - ISSN 1476-4598. - 13:1(2014), p. 160. [10.1186/1476-4598-13-160]

Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells

DI MARO, GENNARO;SALERNO, PAOLO;ORLANDELLA, FRANCESCA MARIA;SANTORO, MASSIMO;
2014

Abstract

Through a transcriptome microarray analysis, we have isolated Anterior gradient protein 2 (AGR2) as a gene up-regulated in papillary thyroid carcinoma (PTC). AGR2 is a disulfide isomerase over-expressed in several human carcinomas and recently linked to endoplasmic reticulum (ER) stress. Here, we analyzed the expression of AGR2 in PTC and its functional role.
2014
Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells / DI MARO, Gennaro; Salerno, Paolo; Unger, Kristian; Orlandella, FRANCESCA MARIA; Monaco, Mario; Chiappetta, Gennaro; Thomas, Gerry; Oczko Wojciechowska, Malgorzata; Masullo, Mariorosario; Jarzab, Barbara; Santoro, Massimo; Salvatore, Giuliana. - In: MOLECULAR CANCER. - ISSN 1476-4598. - 13:1(2014), p. 160. [10.1186/1476-4598-13-160]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/614483
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