SANTORO, MASSIMO
SANTORO, MASSIMO
DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).
2003 Carlomagno, F; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice
2000 Portella, Giuseppe; Borselli, C.; Santoro, Massimo; Gerbasio, D.; D'Armiento, M. R.; Dumont, E. J.; Ledent, C.; Rothstein, J. L.; Vecchio, Giancarlo; Fusco, Alfredo
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade.
2001 Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax
Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.
2003 Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo
Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase
2002 Salvatore, Giuliana; Nagata, S.; Billaud, M.; Santoro, Massimo; Vecchio, Giancarlo; Pastan, I.
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas
2003 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
2002 Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes
2002 Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
The RET receptor: function in development and dysfunction in congenital malformation.
2001 Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M.
RET activation and clinicopathologic features in poorly differentiated thyroid tumors.
2002 Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo
RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
2001 Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2)
2003 Carlomagno, Francesca; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
The oncogene associated with human papillary thyroid carcinoma (PTC) is assigned to chromosome 10 q11-q12 in the same region as multiple endocrine neoplasia type 2A (MEN2A).
1989 Donghi, R.; Sozzi, G.; Pierotti, M. A.; Biunno, I.; Miozzo, M.; Fusco, Alfredo; Grieco, M.; Santoro, Massimo; Vecchio, Giancarlo; Spurr, N. K.
Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo.
1994 Grieco, M.; Cerrato, A.; Santoro, Massimo; Fusco, Alfredo; Melillo, ROSA MARINA; Vecchio, Giancarlo
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.
1990 Grieco, M.; Santoro, Massimo; Berlingieri, M. T.; Melillo, ROSA MARINA; Donghi, R.; Bongarzone, I.; Pierotti, M. A.; Della Porta, G.; Fusco, Alfredo; Vecchio, Giancarlo
TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line
1998 Portella, Giuseppe; Vitagliano, D; Li, Z; Sferratore, F; Santoro, Massimo; Vecchio, Giancarlo; Fusco, Alfredo
RET ONCOGENE ACTIVATION IN HUMAN THYROID NEOPLASMS IS RESTRICTED TO THE PAPILLARY CANCER SUBTYPE
1992 Santoro, Massimo; Carlomagno, Francesca; Hay, I. D.; Herrmann, M. A.; Grieco, M.; Melillo, ROSA MARINA; Pierotti, M. A.; Bongarzone, I.; DELLA PORTA, G.; Berger, N.; Peix, J. L.; Paulin, C.; Fabien, N.; Vecchio, Giancarlo; Jenkins, R. B.; Fusco, Alfredo
RFLP for TaqI of the human thyroid papillary carcinoma (PTC) oncogene.
1988 Radice, P.; Donghi, R.; Pierotti, M. A.; Longoni, A.; Fusco, Alfredo; Grieco, M.; Santoro, Massimo; Vecchio, Giancarlo; Della Porta, G.
Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.
1994 Santoro, Massimo; Dathan, N. A.; Berlingieri, M. T.; Bongarzone, I.; Paulin, C.; Grieco, M.; Pierotti, M. A.; Vecchio, Giancarlo; Fusco, Alfredo
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). | 1.1 Articolo in rivista | 2003 | Carlomagno, F; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo | |
| Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice | 1.1 Articolo in rivista | 2000 | Portella, Giuseppe; Borselli, C.; Santoro, Massimo; Gerbasio, D.; D'Armiento, M. R.; Dumont, E. J.; Ledent, C.; Rothstein, J. L.; Vecchio, Giancarlo; Fusco, Alfredo | |
| The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax | |
| Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes. | 1.1 Articolo in rivista | 2003 | Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo | |
| Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase | 1.1 Articolo in rivista | 2002 | Salvatore, Giuliana; Nagata, S.; Billaud, M.; Santoro, Massimo; Vecchio, Giancarlo; Pastan, I. | |
| Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas | 1.1 Articolo in rivista | 2003 | Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo | |
| The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. | 1.1 Articolo in rivista | 2002 | Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg | |
| The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes | 1.1 Articolo in rivista | 2002 | Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo | |
| The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo | |
| The RET receptor: function in development and dysfunction in congenital malformation. | 1.1 Articolo in rivista | 2001 | Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M. | |
| RET activation and clinicopathologic features in poorly differentiated thyroid tumors. | 1.1 Articolo in rivista | 2002 | Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo | |
| RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho. | 1.1 Articolo in rivista | 2001 | Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo | |
| Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2) | 1.1 Articolo in rivista | 2003 | Carlomagno, Francesca; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo | |
| The oncogene associated with human papillary thyroid carcinoma (PTC) is assigned to chromosome 10 q11-q12 in the same region as multiple endocrine neoplasia type 2A (MEN2A). | 1.1 Articolo in rivista | 1989 | Donghi, R.; Sozzi, G.; Pierotti, M. A.; Biunno, I.; Miozzo, M.; Fusco, Alfredo; Grieco, M.; Santoro, Massimo; Vecchio, Giancarlo; Spurr, N. K. | |
| Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo. | 1.1 Articolo in rivista | 1994 | Grieco, M.; Cerrato, A.; Santoro, Massimo; Fusco, Alfredo; Melillo, ROSA MARINA; Vecchio, Giancarlo | |
| PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. | 1.1 Articolo in rivista | 1990 | Grieco, M.; Santoro, Massimo; Berlingieri, M. T.; Melillo, ROSA MARINA; Donghi, R.; Bongarzone, I.; Pierotti, M. A.; Della Porta, G.; Fusco, Alfredo; Vecchio, Giancarlo | |
| TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line | 1.1 Articolo in rivista | 1998 | Portella, Giuseppe; Vitagliano, D; Li, Z; Sferratore, F; Santoro, Massimo; Vecchio, Giancarlo; Fusco, Alfredo | |
| RET ONCOGENE ACTIVATION IN HUMAN THYROID NEOPLASMS IS RESTRICTED TO THE PAPILLARY CANCER SUBTYPE | 1.1 Articolo in rivista | 1992 | Santoro, Massimo; Carlomagno, Francesca; Hay, I. D.; Herrmann, M. A.; Grieco, M.; Melillo, ROSA MARINA; Pierotti, M. A.; Bongarzone, I.; DELLA PORTA, G.; Berger, N.; Peix, J. L.; Paulin, C.; Fabien, N.; Vecchio, Giancarlo; Jenkins, R. B.; Fusco, Alfredo | |
| RFLP for TaqI of the human thyroid papillary carcinoma (PTC) oncogene. | 1.1 Articolo in rivista | 1988 | Radice, P.; Donghi, R.; Pierotti, M. A.; Longoni, A.; Fusco, Alfredo; Grieco, M.; Santoro, Massimo; Vecchio, Giancarlo; Della Porta, G. | |
| Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma. | 1.1 Articolo in rivista | 1994 | Santoro, Massimo; Dathan, N. A.; Berlingieri, M. T.; Bongarzone, I.; Paulin, C.; Grieco, M.; Pierotti, M. A.; Vecchio, Giancarlo; Fusco, Alfredo |