SANTORO, MASSIMO

SANTORO, MASSIMO  

DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE  

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Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma 1.1 Articolo in rivista 2002 F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo
Onset of Natural Killer Cell Lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway. 1.1 Articolo in rivista 2001 Baldassarre, G.; Fedele, M.; Battista, S.; Vecchione, A.; KLEIN SZANTO, Ajp; Santoro, Massimo; Waldmann, T. A.; Azimi, N.; Croce, C. M.; Fusco, Alfredo
The expression of a truncated HMGI-C gene induces a gigantism associated with lipomatosis 1.1 Articolo in rivista 1999 Battista, S.; Fidanza, V.; Fedele, M.; KLEIN SZANTO, A.; Outwater, E.; Brunner, H.; Santoro, Massimo; Croce, Cm; Fusco, Alfredo
RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions 1.1 Articolo in rivista 2002 B. J., Collins; G., Chiappetta; A. B., Schneider; Santoro, Massimo; F., Pentimalli; L., Fogelfeld; T., Gierlowski; E., Shorefreedman; G., Jaffe; Fusco, Alfredo
RET activation and clinicopathologic features in poorly differentiated thyroid tumors. 1.1 Articolo in rivista 2002 Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo
The RET receptor: function in development and dysfunction in congenital malformation. 1.1 Articolo in rivista 2001 Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M.
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. 1.1 Articolo in rivista 2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes 1.1 Articolo in rivista 2002 Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo
Detection of High Mobility Group I HMGI(Y) Protein in the Diagnosis of Thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma. 1.1 Articolo in rivista 1998 Chiappetta, G; Tallini, G; De Biasio, Mc; Manfioletti, G; Martinez Tello, Fj; Pentimalli, F; de Nigris, F; Mastro, A; Botti, G; Fedele, M; Berger, N; Santoro, Massimo; Giancotti, V; Fusco, Alfredo
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). 1.1 Articolo in rivista 2003 Carlomagno, F; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. 1.1 Articolo in rivista 2001 Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax
Ret-mediated mitogenesis requires Src kinase activity. 1.1 Articolo in rivista 1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo
Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase 1.1 Articolo in rivista 2002 Salvatore, Giuliana; Nagata, S.; Billaud, M.; Santoro, Massimo; Vecchio, Giancarlo; Pastan, I.
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1). 1.1 Articolo in rivista 2002 Baldassarre, G; Bruni, P; Boccia, A; Salvatore, G; Melillo, ROSA MARINA; Motti, Ml; Napolitano, M; Belletti, B; Fusco, Alfredo; Santoro, Massimo; Viglietto, G.
Molecular mechanisms of RET activation in human neoplasia 2.1 Contributo in volume (Capitolo o Saggio) 2002 Santoro, Massimo; Carlomagno, F; Melillo, ROSA MARINA; Vecchio, Giancarlo; Fusco, Alfredo
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas 1.1 Articolo in rivista 2003 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo
Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice 1.1 Articolo in rivista 2000 Portella, Giuseppe; Borselli, C.; Santoro, Massimo; Gerbasio, D.; D'Armiento, M. R.; Dumont, E. J.; Ledent, C.; Rothstein, J. L.; Vecchio, Giancarlo; Fusco, Alfredo
Molecular mechanisms of RET activation in human cancer 2.1 Contributo in volume (Capitolo o Saggio) 2002 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. 1.1 Articolo in rivista 2002 Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels. 1.1 Articolo in rivista 2003 Wang, J; Knauf, Ja; Basu, S; Puxeddu, E; Kuroda, H; Santoro, Massimo; Fusco, Alfredo; Fagin, Ja