SANTORO, MASSIMO
SANTORO, MASSIMO
Dipartimento di Medicina molecolare e Biotecnologie mediche
NCOA4 links iron bioavailability to DNA metabolism
2022 Federico, Giorgia; Carrillo, Federica; Dapporto, Francesca; Chiariello, Mario; Santoro, Massimo; Bellelli, Roberto; Carlomagno, Francesca
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation
2021 Yan, W.; Zhang, L.; Lv, F.; Moccia, M.; Carlomagno, F.; Landry, C.; Santoro, M.; Gosselet, F.; Frett, B.; Li, H. -Y.
Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases
2021 Moccia, M.; Yang, D.; Lakkaniga, N. R.; Frett, B.; Mcconnell, N.; Zhang, L.; Brescia, A.; Federico, G.; Zhang, L.; Salerno, P.; Santoro, M.; Li, H. -Y.; Carlomagno, F.
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose
2022 Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C; Bharate, Jaideep B; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q; Carlomagno, Francesca; Li, Hong-Yu
Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells.
2011 Angrisano, Tiziana; Sacchetti, Silvana; Natale, Francesco; Cerrato, A.; Pero, Raffaela; Keller, Simona; Peluso, S.; Perillo, B.; Avvedimento, VITTORIO ENRICO; Fusco, Alfredo; Bruni, C.; Lembo, Francesca; Santoro, Massimo; Chiariotti, Lorenzo
The importance of the RET gene in thyroid cancer and therapeutic implications
2021 Salvatore, D.; Santoro, M.; Schlumberger, M.
Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1
2017 Moretti, Sonia; Menicali, Elisa; Nucci, Nicole; Voce, Pasquale; Colella, Renato; Melillo, ROSA MARINA; Liotti, Federica; Morelli, Silvia; Fallarino, Francesca; Macchiarulo, Antonio; Santoro, Massimo; Avenia, Nicola; Puxeddu, Efisio
A dual mechanism of activation of the sonic hedgehog pathway in anaplastic thyroid cancer: Crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma
2018 Parascandolo, Alessia; Laukkanen, Mikko O.; de Rosa, Nancy; Ugolini, Clara; Cantisani, MARIA CARMELA; Cirafici, Anna Maria; Basolo, Fulvio; Santoro, Massimo; Castellone, Maria Domenica
Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma
2015 Wells, Samuel A; Asa, Sylvia L; Dralle, Henning; Elisei, Rossella; Evans, Douglas B; Gagel, Robert F; Lee, Nancy; Machens, Andreas; Moley, Jeffrey F; Pacini, Furio; Raue, Friedhelm; Frank Raue, Karin; Robinson, Bruce; Rosenthal, M. Sara; Santoro, Massimo; Schlumberger, Martin; Shah, Manisha; Waguespack, Steven G.
Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms
2019 Affinito, Ornella; Salerno, Paolo; D'Alessio, Alfonso Manuel; Cuomo, Mariella; Florio, Ermanno; Carlomagno, Francesca; Proietti, Agnese; Giannini, Riccardo; Basolo, Fulvio; Chiariotti, Lorenzo; Cocozza, Sergio; Santoro, Massimo
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase
2003 Andreozzi, F; Melillo, ROSA MARINA; Carlomagno, F; Oriente, Francesco; Miele, C; Fiory, Francesca; Santopietro, S; Castellone, Md; Beguinot, Francesco; Santoro, Massimo; Formisano, Pietro
NCOA4 Links Iron Bioavailability to DNA Metabolism
2017 Federico, G; Bellelli, R; Nai, A; Silvestri, L; Camaschella, C; Iolascon, A; Santoro, M; Carlomagno, F
Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma
2015 Castellone, M. D; Laukkanen, M. O; Teramoto, H; Bellelli, Roberto; Alì, G; Fontanini, G; Santoro, Massimo; Gutkind, J. S.
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application
2019 Yan, Wei; Lakkaniga, Naga Rajiv; Carlomagno, Francesca; Santoro, Massimo; Mcdonald, Neil Q.; Lv, Fengping; Gunaganti, Naresh; Frett, Brendan; Li, Hong-Yu
Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology
2020 Moccia, M.; Frett, B.; Zhang, L.; Lakkaniga, N. R.; Briggs, D. C.; Chauhan, R.; Brescia, A.; Federico, G.; Yan, W.; Santoro, M.; Mcdonald, N. Q.; Li, H. -Y.; Carlomagno, F.
Ret gene fusions in malignancies of the thyroid and other tissues
2020 Santoro, M.; Moccia, M.; Federico, G.; Carlomagno, F.
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology
2015 Frett, Brendan; Carlomagno, Francesca; Moccia, Marialuisa; Brescia, Annalisa; Federico, Giorgia; De Falco, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hong yu
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer
2017 De Falco, Valentina; Carlomagno, Francesca; Li, Hong-yu; Santoro, Massimo
Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway.
2015 Visciano, Carla; Liotti, Federica; Prevete, Nella; Cali', G; Franco, R; Collina, F; DE PAULIS, Amato; Marone, Gianni; Santoro, Massimo; Melillo, ROSA MARINA
Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase.
1997 Zhang, L; Martelli, Ml; Battaglia, C; Trapasso, Serena; Tramontano, Donatella; Viglietto, G; Porcellini, Antonio; Santoro, Massimo; Fusco, Alfredo
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| NCOA4 links iron bioavailability to DNA metabolism | 1.1 Articolo in rivista | 2022 | Federico, Giorgia; Carrillo, Federica; Dapporto, Francesca; Chiariello, Mario; Santoro, Massimo; Bellelli, Roberto; Carlomagno, Francesca | |
| Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation | 1.1 Articolo in rivista | 2021 | Yan, W.; Zhang, L.; Lv, F.; Moccia, M.; Carlomagno, F.; Landry, C.; Santoro, M.; Gosselet, F.; Frett, B.; Li, H. -Y. | |
| Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases | 1.1 Articolo in rivista | 2021 | Moccia, M.; Yang, D.; Lakkaniga, N. R.; Frett, B.; Mcconnell, N.; Zhang, L.; Brescia, A.; Federico, G.; Zhang, L.; Salerno, P.; Santoro, M.; Li, H. -Y.; Carlomagno, F. | |
| Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose | 1.1 Articolo in rivista | 2022 | Zhang, Lingtian; Moccia, Marialuisa; Briggs, David C; Bharate, Jaideep B; Lakkaniga, Naga Rajiv; Knowles, Phillip; Yan, Wei; Tran, Phuc; Kharbanda, Anupreet; Wang, Xiuqi; Leung, Yuet-Kin; Frett, Brendan; Santoro, Massimo; Mcdonald, Neil Q; Carlomagno, Francesca; Li, Hong-Yu | |
| Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells. | 1.1 Articolo in rivista | 2011 | Angrisano, Tiziana; Sacchetti, Silvana; Natale, Francesco; Cerrato, A.; Pero, Raffaela; Keller, Simona; Peluso, S.; Perillo, B.; Avvedimento, VITTORIO ENRICO; Fusco, Alfredo; Bruni, C.; Lembo, Francesca; Santoro, Massimo; Chiariotti, Lorenzo | |
| The importance of the RET gene in thyroid cancer and therapeutic implications | 1.1 Articolo in rivista | 2021 | Salvatore, D.; Santoro, M.; Schlumberger, M. | |
| Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1 | 1.1 Articolo in rivista | 2017 | Moretti, Sonia; Menicali, Elisa; Nucci, Nicole; Voce, Pasquale; Colella, Renato; Melillo, ROSA MARINA; Liotti, Federica; Morelli, Silvia; Fallarino, Francesca; Macchiarulo, Antonio; Santoro, Massimo; Avenia, Nicola; Puxeddu, Efisio | |
| A dual mechanism of activation of the sonic hedgehog pathway in anaplastic thyroid cancer: Crosstalk with RAS-BRAF-MEK pathway and ligand secretion by tumor stroma | 1.1 Articolo in rivista | 2018 | Parascandolo, Alessia; Laukkanen, Mikko O.; de Rosa, Nancy; Ugolini, Clara; Cantisani, MARIA CARMELA; Cirafici, Anna Maria; Basolo, Fulvio; Santoro, Massimo; Castellone, Maria Domenica | |
| Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma | 1.1 Articolo in rivista | 2015 | Wells, Samuel A; Asa, Sylvia L; Dralle, Henning; Elisei, Rossella; Evans, Douglas B; Gagel, Robert F; Lee, Nancy; Machens, Andreas; Moley, Jeffrey F; Pacini, Furio; Raue, Friedhelm; Frank Raue, Karin; Robinson, Bruce; Rosenthal, M. Sara; Santoro, Massimo; Schlumberger, Martin; Shah, Manisha; Waguespack, Steven G. | |
| Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms | 1.1 Articolo in rivista | 2019 | Affinito, Ornella; Salerno, Paolo; D'Alessio, Alfonso Manuel; Cuomo, Mariella; Florio, Ermanno; Carlomagno, Francesca; Proietti, Agnese; Giannini, Riccardo; Basolo, Fulvio; Chiariotti, Lorenzo; Cocozza, Sergio; Santoro, Massimo | |
| Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase | 1.1 Articolo in rivista | 2003 | Andreozzi, F; Melillo, ROSA MARINA; Carlomagno, F; Oriente, Francesco; Miele, C; Fiory, Francesca; Santopietro, S; Castellone, Md; Beguinot, Francesco; Santoro, Massimo; Formisano, Pietro | |
| NCOA4 Links Iron Bioavailability to DNA Metabolism | 1.1 Articolo in rivista | 2017 | Federico, G; Bellelli, R; Nai, A; Silvestri, L; Camaschella, C; Iolascon, A; Santoro, M; Carlomagno, F | |
| Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma | 1.1 Articolo in rivista | 2015 | Castellone, M. D; Laukkanen, M. O; Teramoto, H; Bellelli, Roberto; Alì, G; Fontanini, G; Santoro, Massimo; Gutkind, J. S. | |
| Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application | 1.1 Articolo in rivista | 2019 | Yan, Wei; Lakkaniga, Naga Rajiv; Carlomagno, Francesca; Santoro, Massimo; Mcdonald, Neil Q.; Lv, Fengping; Gunaganti, Naresh; Frett, Brendan; Li, Hong-Yu | |
| Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology | 1.1 Articolo in rivista | 2020 | Moccia, M.; Frett, B.; Zhang, L.; Lakkaniga, N. R.; Briggs, D. C.; Chauhan, R.; Brescia, A.; Federico, G.; Yan, W.; Santoro, M.; Mcdonald, N. Q.; Li, H. -Y.; Carlomagno, F. | |
| Ret gene fusions in malignancies of the thyroid and other tissues | 1.1 Articolo in rivista | 2020 | Santoro, M.; Moccia, M.; Federico, G.; Carlomagno, F. | |
| Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology | 1.1 Articolo in rivista | 2015 | Frett, Brendan; Carlomagno, Francesca; Moccia, Marialuisa; Brescia, Annalisa; Federico, Giorgia; De Falco, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hong yu | |
| The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer | 1.1 Articolo in rivista | 2017 | De Falco, Valentina; Carlomagno, Francesca; Li, Hong-yu; Santoro, Massimo | |
| Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway. | 1.1 Articolo in rivista | 2015 | Visciano, Carla; Liotti, Federica; Prevete, Nella; Cali', G; Franco, R; Collina, F; DE PAULIS, Amato; Marone, Gianni; Santoro, Massimo; Melillo, ROSA MARINA | |
| Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase. | 1.1 Articolo in rivista | 1997 | Zhang, L; Martelli, Ml; Battaglia, C; Trapasso, Serena; Tramontano, Donatella; Viglietto, G; Porcellini, Antonio; Santoro, Massimo; Fusco, Alfredo |