Palytoxin and ovatoxins are posing a serious concern to human health in the Mediterranean area as they are the major toxins produced by Ostreopsis cf. ovata, a benthic dinoflagellate that since late 90’s repeatedly blooms along the Mediterranean coasts of Italy, France, Spain, and Greece. In order to prevent the potential sanitary risks associated with consumption of palytoxin contaminated seafood, the European Food Safety Authority (EFSA) indicated the need for efficient, rapid and sensitive methods to monitor the presence of palytoxin-like compounds in seafood. In the present study, the best conditions for extraction and clean-up of palytoxin from mussels and their determination using LC coupled to high resolution mass spectrometry (HR-MS) are presented

A New High Resolution LC-MS Method for Identification, Quantification and Monitoring of Palytoxin-like Compounds in Molluscs

CIMINIELLO, PATRIZIA;DELL'AVERSANO, CARMELA;DELLO IACOVO, EMMA;FATTORUSSO, ERNESTO;FORINO, MARTINO;TARTAGLIONE, LUCIANA
2013

Abstract

Palytoxin and ovatoxins are posing a serious concern to human health in the Mediterranean area as they are the major toxins produced by Ostreopsis cf. ovata, a benthic dinoflagellate that since late 90’s repeatedly blooms along the Mediterranean coasts of Italy, France, Spain, and Greece. In order to prevent the potential sanitary risks associated with consumption of palytoxin contaminated seafood, the European Food Safety Authority (EFSA) indicated the need for efficient, rapid and sensitive methods to monitor the presence of palytoxin-like compounds in seafood. In the present study, the best conditions for extraction and clean-up of palytoxin from mussels and their determination using LC coupled to high resolution mass spectrometry (HR-MS) are presented
9780646929934
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/596572
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