Molecules able to interfere in miRNA genesis and function are potent tools to unravel maturation and processing pathways. Antisense oligonucleotides or analogs are actually employed for the inhibition of miRNA function. Here we illustrate how Peptide Nucleic Acids oligomers targeting pre-miRNA are exploited to inhibit miRNA maturation.

Inhibition of miRNA maturation by peptide nucleic acids / Concetta, Avitabile; Enrica, Fabbri; Nicoletta, Bianchi; Roberto, Gambari; Romanelli, Alessandra. - 1095:(2014), pp. 157-164. [10.1007/978-1-62703-703-7-13]

Inhibition of miRNA maturation by peptide nucleic acids

ROMANELLI, ALESSANDRA
2014

Abstract

Molecules able to interfere in miRNA genesis and function are potent tools to unravel maturation and processing pathways. Antisense oligonucleotides or analogs are actually employed for the inhibition of miRNA function. Here we illustrate how Peptide Nucleic Acids oligomers targeting pre-miRNA are exploited to inhibit miRNA maturation.
2014
9781627037020
Inhibition of miRNA maturation by peptide nucleic acids / Concetta, Avitabile; Enrica, Fabbri; Nicoletta, Bianchi; Roberto, Gambari; Romanelli, Alessandra. - 1095:(2014), pp. 157-164. [10.1007/978-1-62703-703-7-13]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/586971
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 6
social impact