Aerobic bacterial degradation of aromatic hydrocarbons is generally divided into two major routes, the so-called upper pathway, which leads to the formation of partially oxidized aromatic intermediates, and a lower pathway, which uses dihydroxylated aromatic molecules. These activated aromatic compounds undergo ring cleavage reactions and are further processed to give molecules that can eventually enter the citric acid cycle. Monooxygenases are key enzymes in the upper pathway and catalyze hydroxylation of the aromatic ring at different positions Pseudomonas stutzeri OX1 is able to grow on a wide spectrum of aromatics, including phenol, cresols, and dimethylphenols, but also on nonhydroxylated molecules such as toluene, o-xylene, and benzene. Two different monooxygenases have been found in the genome of P. stutzeri OX1, phenol hydroxylase (PH) (1) and toluene o-xylene monooxygenase (ToMO) .

RECONSTITUTED RECOMBINANT PHENOL HYDROXYLASE FROM P. STUTZERI OX1 / Scognamiglio, Roberta; Viviana, Izzo; Alfieri, Fabiana; Carpentieri, Andrea; Giovanna Gomez, D'Ayala; Smith, Ornella; DI DONATO, Alberto. - (2002). (Intervento presentato al convegno 47° Congresso Nazionale SIB tenutosi a Palermo nel 06/2002).

RECONSTITUTED RECOMBINANT PHENOL HYDROXYLASE FROM P. STUTZERI OX1

SCOGNAMIGLIO, ROBERTA;ALFIERI, FABIANA;CARPENTIERI, ANDREA;SMITH, ORNELLA;DI DONATO, ALBERTO
2002

Abstract

Aerobic bacterial degradation of aromatic hydrocarbons is generally divided into two major routes, the so-called upper pathway, which leads to the formation of partially oxidized aromatic intermediates, and a lower pathway, which uses dihydroxylated aromatic molecules. These activated aromatic compounds undergo ring cleavage reactions and are further processed to give molecules that can eventually enter the citric acid cycle. Monooxygenases are key enzymes in the upper pathway and catalyze hydroxylation of the aromatic ring at different positions Pseudomonas stutzeri OX1 is able to grow on a wide spectrum of aromatics, including phenol, cresols, and dimethylphenols, but also on nonhydroxylated molecules such as toluene, o-xylene, and benzene. Two different monooxygenases have been found in the genome of P. stutzeri OX1, phenol hydroxylase (PH) (1) and toluene o-xylene monooxygenase (ToMO) .
2002
RECONSTITUTED RECOMBINANT PHENOL HYDROXYLASE FROM P. STUTZERI OX1 / Scognamiglio, Roberta; Viviana, Izzo; Alfieri, Fabiana; Carpentieri, Andrea; Giovanna Gomez, D'Ayala; Smith, Ornella; DI DONATO, Alberto. - (2002). (Intervento presentato al convegno 47° Congresso Nazionale SIB tenutosi a Palermo nel 06/2002).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/560308
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