Introduction. Acne can produce permanent scars that are surprisingly difficult to treat. At present, there are many options available for acne scarring treatment. A relatively new treatment, called skin needling, seems to be appropriate for the treatment of rolling scars in acne. Autologous platelet gel is created by pheresing platelet-rich plasma from whole blood and combined it with thrombin and calcium or other activators to form a coagulum. Platelet gel contains autologous growth factors which act synergistically to accelerate the rate and degree of tissue regeneration, improving wound healing. The aim of this study was to demonstrate the usefulness of the combined use of skin needling and an autologous platelet gel in acne scarring treatment. Methods. 10 patients (6 female, 4 males; age range 18-45) with acne rolling scars were included. Each patient was treated with a specific tool in two session. Using digital cameras, photos of all patients were taken to evaluate scar depth and, in five patients, silicone rubber was used to make a microrelief impression of the scar.The photographic data were analized by using the Sign’s Test (alfa < 0.05); cutaneous’ casts data were analized by using the Fast Fourier Transform (FFT). Results. Analysis of the patient photographs, supported by the sign test and of the degree of irregularity of the surface microrelief, supported by FFT, showed that after only two sessions the severity grade of rolling scars in all patients was greatly reduced and there was an overall aesthetic improvement. Conclusion. The present study demonstrate that the combined use of skin needling and an autologous platelet gel has a great effect in improving acne rolling scars and has undisputable advantages over other procedures.
Combined use of skin needling and an autologous platelet gel in acne scarring treatment / Fabbrocini, Gabriella; Annunziata, Maria; Vincenza, D’Arco; DE VITA, Valerio; Nunzio, Fardella; Maria Chiara, Mauriello; Pastore, Francesco; Elio, D’Agostino; Sepulveres, Rossana; Aurioso, Gennaro; Monfrecola, Giuseppe. - (2010). (Intervento presentato al convegno 19th Congress of the European Academy of dermatology and Venereology tenutosi a Gothenburg, Sweden nel 6-10 Ottobre 2010).
Combined use of skin needling and an autologous platelet gel in acne scarring treatment
FABBROCINI, GABRIELLA;ANNUNZIATA, Maria;DE VITA, VALERIO;PASTORE, FRANCESCO;SEPULVERES, ROSSANA;AURIOSO, GENNARO;MONFRECOLA, GIUSEPPE
2010
Abstract
Introduction. Acne can produce permanent scars that are surprisingly difficult to treat. At present, there are many options available for acne scarring treatment. A relatively new treatment, called skin needling, seems to be appropriate for the treatment of rolling scars in acne. Autologous platelet gel is created by pheresing platelet-rich plasma from whole blood and combined it with thrombin and calcium or other activators to form a coagulum. Platelet gel contains autologous growth factors which act synergistically to accelerate the rate and degree of tissue regeneration, improving wound healing. The aim of this study was to demonstrate the usefulness of the combined use of skin needling and an autologous platelet gel in acne scarring treatment. Methods. 10 patients (6 female, 4 males; age range 18-45) with acne rolling scars were included. Each patient was treated with a specific tool in two session. Using digital cameras, photos of all patients were taken to evaluate scar depth and, in five patients, silicone rubber was used to make a microrelief impression of the scar.The photographic data were analized by using the Sign’s Test (alfa < 0.05); cutaneous’ casts data were analized by using the Fast Fourier Transform (FFT). Results. Analysis of the patient photographs, supported by the sign test and of the degree of irregularity of the surface microrelief, supported by FFT, showed that after only two sessions the severity grade of rolling scars in all patients was greatly reduced and there was an overall aesthetic improvement. Conclusion. The present study demonstrate that the combined use of skin needling and an autologous platelet gel has a great effect in improving acne rolling scars and has undisputable advantages over other procedures.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
