Evaluation of quantitative parameters about tumour perfusion, such as arterial blood flow (BFa), by CT perfusion is gaining acceptance in clinical applications. ROI based analysis can be considered the gold standard technique to derive quantitative parameters, although it does not allow to depict the heterogeneous vascularisation of tumour tissue. On the contrary, pixel by pixel analysis, which has this potentiality,leads only to qualitative depiction of tumour perfusion by means of colour scale since still lacks of robust processing methods. In this work, we propose an algorithm for parametric estimation (pixel by pixel) of BFa values and used it for the analysis of a group of seventeen patients with primary liver tumour. Then, we compared obtained BFa values with those estimated by a ROI based approach, by using the same image processing, to investigate the reliability of parametric maps computed with the algorithm developed.
Reliability of perfusion maps in HCC patients / Michela, D'Antò; Francesco, Fiore; Romano, Maria; Bifulco, Paolo; Cesarelli, Mario. - (2012), pp. 1-2. (Intervento presentato al convegno GNB2012 tenutosi a Rome, Italy nel June 26th-29th 2012).
Reliability of perfusion maps in HCC patients
ROMANO, MARIA;BIFULCO, PAOLO;CESARELLI, MARIO
2012
Abstract
Evaluation of quantitative parameters about tumour perfusion, such as arterial blood flow (BFa), by CT perfusion is gaining acceptance in clinical applications. ROI based analysis can be considered the gold standard technique to derive quantitative parameters, although it does not allow to depict the heterogeneous vascularisation of tumour tissue. On the contrary, pixel by pixel analysis, which has this potentiality,leads only to qualitative depiction of tumour perfusion by means of colour scale since still lacks of robust processing methods. In this work, we propose an algorithm for parametric estimation (pixel by pixel) of BFa values and used it for the analysis of a group of seventeen patients with primary liver tumour. Then, we compared obtained BFa values with those estimated by a ROI based approach, by using the same image processing, to investigate the reliability of parametric maps computed with the algorithm developed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.