The purpose of this experiment was to examine the effects of intraventricular injections of glutamate and aspartate on the gait of animals rendered ataxic by the administration of acrylamide. Contrary to their previously reported corrective influence on ataxia induced by 3-acetyl pyridine, these amino acids did not modify the ataxic gait of acrylamide treated animals. This suggests that glutamate and aspartate can act in cerebellar but not in peripheral types of ataxia in animals.
Glutamate and aspartate do not modify the ataxic gait of acrylamide treated animals / DE MICHELE, Giuseppe; F. B., Jolicoeur; A., Barbeau. - In: CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES. - ISSN 0317-1671. - STAMPA. - 9:(1982), pp. 179-180.
Glutamate and aspartate do not modify the ataxic gait of acrylamide treated animals.
DE MICHELE, GIUSEPPE;
1982
Abstract
The purpose of this experiment was to examine the effects of intraventricular injections of glutamate and aspartate on the gait of animals rendered ataxic by the administration of acrylamide. Contrary to their previously reported corrective influence on ataxia induced by 3-acetyl pyridine, these amino acids did not modify the ataxic gait of acrylamide treated animals. This suggests that glutamate and aspartate can act in cerebellar but not in peripheral types of ataxia in animals.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.