Thanks to its physical and chemical structure, shed snake skin can be used as a model membrane for human skin in in vitro drug delivery experiments. The progesterone mass transfer through Bitis gabonica skin has been studied using a suitable diffusion glass cell. A lag time of 5.7 hours, representative the unsteady diffusion regime, has been observed. After this lag time, the system reaches the steady-state condition during which the diffusion coefficient and the partition coefficient of progesterone in the system have been calculated by the integration of Fick’s laws

Progesterone diffusion through snake skin as ahuman model membrane / Tagliaferri, C.; Gallo, Marianna; Stanzione, V.; Nigro, Roberto. - In: INTERNATIONAL JOURNAL OF DESIGN ENGINEERING. - ISSN 1751-5874. - 4:2(2011), pp. 186-196.

Progesterone diffusion through snake skin as ahuman model membrane

GALLO, MARIANNA;NIGRO, ROBERTO
2011

Abstract

Thanks to its physical and chemical structure, shed snake skin can be used as a model membrane for human skin in in vitro drug delivery experiments. The progesterone mass transfer through Bitis gabonica skin has been studied using a suitable diffusion glass cell. A lag time of 5.7 hours, representative the unsteady diffusion regime, has been observed. After this lag time, the system reaches the steady-state condition during which the diffusion coefficient and the partition coefficient of progesterone in the system have been calculated by the integration of Fick’s laws
2011
Progesterone diffusion through snake skin as ahuman model membrane / Tagliaferri, C.; Gallo, Marianna; Stanzione, V.; Nigro, Roberto. - In: INTERNATIONAL JOURNAL OF DESIGN ENGINEERING. - ISSN 1751-5874. - 4:2(2011), pp. 186-196.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/455138
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