Severe hemophilia is complicated by recurrent spontaneous joint bleedings, which lead to severe secondary arthrosis, defined as hemophilic arthropathy. Joint pain, unresponsive to medical treatment and impaired function are indications for total knee replacement. A well–balanced homeostasis is the basic requirement for successful operative interventions. The aim of our study is to evaluate the results of a combined series of total knee replacements in 25 patients with severe hemophilia A and one patient with severe hemophilia B, treated at University Orthopaedic Departments of Naples and Bari from 1992 to 2006. We evaluated patients according Knee Score. Review of the patients over a period of 85 months (12–156 months) after operation showed dramatic reduction of pain and maintenance of a satisfactory range of movement. The frequency of hemarthrosis was also markedly reduced and the requirements for replacement FVIII/IX concentrate in the years after operation fell substantially. On the whole, an improvement of the Knee Score from 37 (pre-operative) to 87 (post-operative) has been recorded. In our experience total knee replacement led to a significant clinical improvement in all the patients, with relevant impact on quality of life.
Total knee arthroplasty in hemophilic arthropathy: long-term follow up / Ruosi, Carlo; M. G., Lettera; D., Marinò; L., Sannino; A., Coppola; V., Patella; B., Moretti; A., Spinarelli; V., Pesce; I., Stolfa; A., Piazzolla; V., Mascolo. - In: HAEMOPHILIA. - ISSN 1351-8216. - STAMPA. - 14:2(2008), pp. 411-411.
Total knee arthroplasty in hemophilic arthropathy: long-term follow up
RUOSI, CARLO;
2008
Abstract
Severe hemophilia is complicated by recurrent spontaneous joint bleedings, which lead to severe secondary arthrosis, defined as hemophilic arthropathy. Joint pain, unresponsive to medical treatment and impaired function are indications for total knee replacement. A well–balanced homeostasis is the basic requirement for successful operative interventions. The aim of our study is to evaluate the results of a combined series of total knee replacements in 25 patients with severe hemophilia A and one patient with severe hemophilia B, treated at University Orthopaedic Departments of Naples and Bari from 1992 to 2006. We evaluated patients according Knee Score. Review of the patients over a period of 85 months (12–156 months) after operation showed dramatic reduction of pain and maintenance of a satisfactory range of movement. The frequency of hemarthrosis was also markedly reduced and the requirements for replacement FVIII/IX concentrate in the years after operation fell substantially. On the whole, an improvement of the Knee Score from 37 (pre-operative) to 87 (post-operative) has been recorded. In our experience total knee replacement led to a significant clinical improvement in all the patients, with relevant impact on quality of life.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.