The influence of baseline parameters on changes in international prostate symptom score with dutasteride, tamsulosin, and combination therapy among men with symptomatic benign prostatic hyperplasia and an enlarged prostate: 2-year data from the CombAT study

The aim of the 4-yr Combination of Avodart and Tamsulosin (CombAT) study is to investigate whether combinationtherapy with the alpha-blocker tamsulosin and the dual 5-ARI dutasteride is more effective thaneithermonotherapy alone for improvement of symptoms and for long-term clinical outcomes of acute urinary retention (AUR) and BPH-related prostatic surgery in men with moderate- to-severe symptoms of BPH and prostatic enlargement