Novel nucleolipid-based nanovectors able to coordi-nate Ru(III) as potential anticancer agents have been prepared following a straightforward and efficient syn-thetic strategy. A combined approach, involving dynamic light scattering (DLS) and small-angle neutron scattering (SANS) measurements, has provided a detailed microstructural characterization of the self-assembled systems, mainly organized in the form of large vesicles.
Novel Nucleoside-based Complexes of Ruthenium (III) as Potential Antitumoral Agents / Simeone, Luca; C., Coppola; Mangiapia, Gaetano; A., Costantino; Paduano, Luigi; DE NAPOLI, Lorenzo; Montesarchio, Daniela. - (2010). (Intervento presentato al convegno XIX International Round Table on Nucleosides, Nucleotides and Nucleic Acids tenutosi a Lione (Francia) nel 29/8-3/9/2010).
Novel Nucleoside-based Complexes of Ruthenium (III) as Potential Antitumoral Agents
SIMEONE, LUCA;MANGIAPIA, GAETANO;PADUANO, LUIGI;DE NAPOLI, LORENZO;MONTESARCHIO, DANIELA
2010
Abstract
Novel nucleolipid-based nanovectors able to coordi-nate Ru(III) as potential anticancer agents have been prepared following a straightforward and efficient syn-thetic strategy. A combined approach, involving dynamic light scattering (DLS) and small-angle neutron scattering (SANS) measurements, has provided a detailed microstructural characterization of the self-assembled systems, mainly organized in the form of large vesicles.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.