Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species. Being the major heterochromatin constituents, satellite DNAs serve important roles in heterochromatin regulation in insect in general. Their expression occurs in all developmental stages, being the highest during embryogenesis. Satellite DNA transcrips range from small RNAs, corresponding in size to siRNA, and piwiRNAs, to large, a few Kb long RNAs. The long transcripts are preferentially nonpolyadenylated and remain in the nucleus. The actively regulated expression of satDNAs by cis or trans elements as well as by environmental stress, rather than constitutive transcription, speaks in favour of their involvement in differentiation, development, and environmental response.
Transcription of satellite DNAs in insects / Z., Pezer; J., Brajkovic; Feliciello, Isidoro; D., Ugarkovic. - STAMPA. - 51:(2011), pp. 161-178. [10.1007/978-3-642-16502-3]
Transcription of satellite DNAs in insects
FELICIELLO, ISIDORO;
2011
Abstract
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species. Being the major heterochromatin constituents, satellite DNAs serve important roles in heterochromatin regulation in insect in general. Their expression occurs in all developmental stages, being the highest during embryogenesis. Satellite DNA transcrips range from small RNAs, corresponding in size to siRNA, and piwiRNAs, to large, a few Kb long RNAs. The long transcripts are preferentially nonpolyadenylated and remain in the nucleus. The actively regulated expression of satDNAs by cis or trans elements as well as by environmental stress, rather than constitutive transcription, speaks in favour of their involvement in differentiation, development, and environmental response.File | Dimensione | Formato | |
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