Four new jaspamide derivs. (e.g. I, jaspamide M) with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analalysis. A structure-activity relationship analalysis on all natural jaspamides is also reported
Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans / F., Gala; D'Auria, MARIA VALERIA; DE MARINO, Simona; Sepe, Valentina; Zollo, Franco; C. D., Smith; S. N., Keller; Zampella, Angela. - In: TETRAHEDRON. - ISSN 0040-4020. - 65:1(2009), pp. 51-56. [10.1016/j.tet.2008.10.076]
Jaspamides M-P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans
D'AURIA, MARIA VALERIA;DE MARINO, SIMONA;SEPE, VALENTINA;ZOLLO, FRANCO;ZAMPELLA, ANGELA
2009
Abstract
Four new jaspamide derivs. (e.g. I, jaspamide M) with antimicrofilament activity were isolated from the marine sponge Jaspis splendans. Their structures were elucidated by NMR and MS analalysis. A structure-activity relationship analalysis on all natural jaspamides is also reportedFile in questo prodotto:
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