Frataxin is a protein responsible for the Friedreich ataxia. Frataxin is involved in iron homeostasis and in iron-sulfur assembly. It has been suggested that frataxin acts as an iron chaperone in the monomeric form and as iron storage in the oligomeric state. We present a structural study of metal ion iteraction with this protein.
The structural characterization of frataxin ion binding sites / Franzese, Marisa; S., Adinolfi; A., Pastore; Mazzarella, Lelio; Sica, Filomena. - STAMPA. - (2006), pp. 9-9. (Intervento presentato al convegno 5th International workshop on Structural characterization of proteins by NMR, X-RAY diffraction and computational methods tenutosi a San Vito di Cadore nel june 16-18, 2006).
The structural characterization of frataxin ion binding sites
FRANZESE, MARISA;MAZZARELLA, LELIO;SICA, FILOMENA
2006
Abstract
Frataxin is a protein responsible for the Friedreich ataxia. Frataxin is involved in iron homeostasis and in iron-sulfur assembly. It has been suggested that frataxin acts as an iron chaperone in the monomeric form and as iron storage in the oligomeric state. We present a structural study of metal ion iteraction with this protein.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
