SICA, FILOMENA
SICA, FILOMENA
Dipartimento di Scienze chimiche
Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study
2023 Troisi, R.; Galardo, F.; Ferraro, G.; Sica, F.; Merlino, A.
Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands
2021 Troisi, Romualdo; Balasco, Nicole; Autiero, Ida; Vitagliano, Luigi; Sica, Filomena
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers
2022 Troisi, Romualdo; Riccardi, Claudia; Pérez de Carvasal, Kévan; Smietana, Michael; Morvan, François; Del Vecchio, Pompea; Montesarchio, Daniela; Sica, Filomena
Aptamers: Functional-Structural Studies and Biomedical Applications
2022 Troisi, Romualdo; Sica, Filomena
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin
2021 Troisi, Romualdo; Balasco, Nicole; Santamaria, Andreas; Vitagliano, Luigi; Sica, Filomena
Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases
2022 Culurciello, Rosanna; Bosso, Andrea; Troisi, Romualdo; Barrella, Valentina; Di Nardo, Ilaria; Borriello, Margherita; Gaglione, Rosa; Pistorio, Valeria; Aceto, Serena; Cafaro, Valeria; Notomista, Eugenio; Sica, Filomena; Arciello, Angela; Pizzo, Elio
Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding.
2016 RUSSO KRAUSS, Irene; Vera, Spiridonova; Pica, Andrea; Napolitano, Valeria; Sica, Filomena
Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12
2021 Smirnov, Igor; Kolganova, Natalia; Troisi, Romualdo; Sica, Filomena; Timofeev, Edward
Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases
2015 Russo Krauss, I; Merlino, A; Pica, A; Rullo, R; Bertoni, A; Capasso, A; Amato, M; Riccitiello, Francesco; De Vendittis, E; Sica, F.
New structural information expands the understanding of the thrombin modulation with oligonucleotide aptamers
2020 Sica, Filomena
Simultaneous binding of aptamers at the two exosites of thrombin: structural and dynamics studies
2020 Sica, F.
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites
2021 Troisi, R.; Balasco, N.; Vitagliano, L.; Sica, F.
Structure–Activity Relationship Study of a Potent α-Thrombin Binding Aptamer Incorporating Hexitol Nucleotides
2020 De Fenza, M.; Eremeeva, E.; Troisi, R.; Yang, H.; Esposito, A.; Sica, F.; Herdewijn, P.; D'Alonzo, D.; Guaragna, A.
Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability
2014 Merlino, Antonello; RUSSO KRAUSS, Irene; Castellano, I; Ruocco, MARIA ROSARIA; Capasso, Alessandra; DE VENDITTIS, Emmanuele; Rossi, B; Sica, Filomena
The cold way for glutathione biosynthesis in the psychrophile Pseudoalteromonas haloplanktis. Redundancy and reaction rates
2016 Albino, Antonella; DE ANGELIS, Amalia; Rullo, Rosario; Maranta, Chiara; Capasso, Alessandra; Ruocco, MARIA ROSARIA; Sica, Filomena; DE VENDITTIS, Emmanuele
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers
2018 Russo Krauss, Irene; Napolitano, Valeria; Petraccone, Luigi; Troisi, Romualdo; Spiridonova, Vera; Mattia, Carlo Andrea; Sica, Filomena
Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer
2018 Troisi, Romualdo; Napolitano, Valeria; Spiridonova, Vera; RUSSO KRAUSS, Irene; Sica, Filomena
Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers
2017 Pica, Andrea; RUSSO KRAUSS, Irene; Parente, Valeria; Tateishi Karimata, Hisae; Nagatoishi, Satoru; Tsumoto, Kouhei; Sugimoto, Naoki; Sica, Filomena
High yield purification and first structural characterization of the full-length bacterial toxin CNF1
2018 Colarusso, Andrea; Caterino, Marco; Fabbri, Alessia; Fiorentini, Carla; Vergara, Alessandro; Sica, Filomena; Parrilli, Ermenegilda; Tutino, Maria Luisa
Structural basis for the recognition of human α-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials
2017 Troisi, R.; Russo Krauss, I.; Napolitano, V.; Sica, F.
Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
---|---|---|---|---|
Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study | 1.1 Articolo in rivista | 2023 | Troisi, R.; Galardo, F.; Ferraro, G.; Sica, F.; Merlino, A. | |
Exosite Binding in Thrombin: A Global Structural/Dynamic Overview of Complexes with Aptamers and Other Ligands | 1.1 Articolo in rivista | 2021 | Troisi, Romualdo; Balasco, Nicole; Autiero, Ida; Vitagliano, Luigi; Sica, Filomena | |
A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers | 1.1 Articolo in rivista | 2022 | Troisi, Romualdo; Riccardi, Claudia; Pérez de Carvasal, Kévan; Smietana, Michael; Morvan, François; Del Vecchio, Pompea; Montesarchio, Daniela; Sica, Filomena | |
Aptamers: Functional-Structural Studies and Biomedical Applications | 1.1 Articolo in rivista | 2022 | Troisi, Romualdo; Sica, Filomena | |
Structural and functional analysis of the simultaneous binding of two duplex/quadruplex aptamers to human α-thrombin | 1.1 Articolo in rivista | 2021 | Troisi, Romualdo; Balasco, Nicole; Santamaria, Andreas; Vitagliano, Luigi; Sica, Filomena | |
Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases | 1.1 Articolo in rivista | 2022 | Culurciello, Rosanna; Bosso, Andrea; Troisi, Romualdo; Barrella, Valentina; Di Nardo, Ilaria; Borriello, Margherita; Gaglione, Rosa; Pistorio, Valeria; Aceto, Serena; Cafaro, Valeria; Notomista, Eugenio; Sica, Filomena; Arciello, Angela; Pizzo, Elio | |
Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding. | 1.1 Articolo in rivista | 2016 | RUSSO KRAUSS, Irene; Vera, Spiridonova; Pica, Andrea; Napolitano, Valeria; Sica, Filomena | |
Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12 | 1.1 Articolo in rivista | 2021 | Smirnov, Igor; Kolganova, Natalia; Troisi, Romualdo; Sica, Filomena; Timofeev, Edward | |
Fine tuning of metal-specific activity in the Mn-like group of cambialistic superoxide dismutases | 1.1 Articolo in rivista | 2015 | Russo Krauss, I; Merlino, A; Pica, A; Rullo, R; Bertoni, A; Capasso, A; Amato, M; Riccitiello, Francesco; De Vendittis, E; Sica, F. | |
New structural information expands the understanding of the thrombin modulation with oligonucleotide aptamers | 4.2 Abstract in Atti di convegno | 2020 | Sica, Filomena | |
Simultaneous binding of aptamers at the two exosites of thrombin: structural and dynamics studies | 4.2 Abstract in Atti di convegno | 2020 | Sica, F. | |
Molecular dynamics simulations of human α-thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites | 1.1 Articolo in rivista | 2021 | Troisi, R.; Balasco, N.; Vitagliano, L.; Sica, F. | |
Structure–Activity Relationship Study of a Potent α-Thrombin Binding Aptamer Incorporating Hexitol Nucleotides | 1.1 Articolo in rivista | 2020 | De Fenza, M.; Eremeeva, E.; Troisi, R.; Yang, H.; Esposito, A.; Sica, F.; Herdewijn, P.; D'Alonzo, D.; Guaragna, A. | |
Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability | 1.1 Articolo in rivista | 2014 | Merlino, Antonello; RUSSO KRAUSS, Irene; Castellano, I; Ruocco, MARIA ROSARIA; Capasso, Alessandra; DE VENDITTIS, Emmanuele; Rossi, B; Sica, Filomena | |
The cold way for glutathione biosynthesis in the psychrophile Pseudoalteromonas haloplanktis. Redundancy and reaction rates | 1.1 Articolo in rivista | 2016 | Albino, Antonella; DE ANGELIS, Amalia; Rullo, Rosario; Maranta, Chiara; Capasso, Alessandra; Ruocco, MARIA ROSARIA; Sica, Filomena; DE VENDITTIS, Emmanuele | |
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers | 1.1 Articolo in rivista | 2018 | Russo Krauss, Irene; Napolitano, Valeria; Petraccone, Luigi; Troisi, Romualdo; Spiridonova, Vera; Mattia, Carlo Andrea; Sica, Filomena | |
Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer | 1.1 Articolo in rivista | 2018 | Troisi, Romualdo; Napolitano, Valeria; Spiridonova, Vera; RUSSO KRAUSS, Irene; Sica, Filomena | |
Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers | 1.1 Articolo in rivista | 2017 | Pica, Andrea; RUSSO KRAUSS, Irene; Parente, Valeria; Tateishi Karimata, Hisae; Nagatoishi, Satoru; Tsumoto, Kouhei; Sugimoto, Naoki; Sica, Filomena | |
High yield purification and first structural characterization of the full-length bacterial toxin CNF1 | 1.1 Articolo in rivista | 2018 | Colarusso, Andrea; Caterino, Marco; Fabbri, Alessia; Fiorentini, Carla; Vergara, Alessandro; Sica, Filomena; Parrilli, Ermenegilda; Tutino, Maria Luisa | |
Structural basis for the recognition of human α-thrombin by NU172: the only thrombin binding aptamer currently in phase II clinical trials | 4.2 Abstract in Atti di convegno | 2017 | Troisi, R.; Russo Krauss, I.; Napolitano, V.; Sica, F. |