In this paper we report on the liquid chromatography tandem mass spectrometry (LC-MS) investigation of plankton samples collected in summer 2006 along the Ligurian coasts, in coincidence with a massive bloom of the tropical microalga Ostreopsis ovata. LC-MS analyses indicated the occurrence of putative palytoxin along with a much more abundant palytoxin-like compound never reported so far, that we named ovatoxin-a. On the basis of molecular formula, fragmentation pattern, and chromatographic behaviour, the structure of ovatoxin-a appeared to be strictly related to palytoxin’s. We report also on the analysis of cultured O. ovata which was most necessary to unequivocally demonstrate that putative palytoxin and ovatoxin-a contained in field samples were actually produced by O. ovata itself.

Putative Palytoxin and its new analogue, Ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak

CIMINIELLO, PATRIZIA;DELL'AVERSANO, CARMELA;FATTORUSSO, ERNESTO;FORINO, MARTINO;TARTAGLIONE, LUCIANA;
2008

Abstract

In this paper we report on the liquid chromatography tandem mass spectrometry (LC-MS) investigation of plankton samples collected in summer 2006 along the Ligurian coasts, in coincidence with a massive bloom of the tropical microalga Ostreopsis ovata. LC-MS analyses indicated the occurrence of putative palytoxin along with a much more abundant palytoxin-like compound never reported so far, that we named ovatoxin-a. On the basis of molecular formula, fragmentation pattern, and chromatographic behaviour, the structure of ovatoxin-a appeared to be strictly related to palytoxin’s. We report also on the analysis of cultured O. ovata which was most necessary to unequivocally demonstrate that putative palytoxin and ovatoxin-a contained in field samples were actually produced by O. ovata itself.
File in questo prodotto:
File Dimensione Formato  
ovatoxin-a.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Accesso privato/ristretto
Dimensione 396.24 kB
Formato Adobe PDF
396.24 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/205111
Citazioni
  • ???jsp.display-item.citation.pmc??? 28
  • Scopus 177
  • ???jsp.display-item.citation.isi??? 174
social impact