The diarrhetic shellfish toxin composition in the digestive glands of mussels collected in June 2001 from the Northern Adriatic sea was investigated by high performance liquid chromatography coupled with electrospray ion trap mass spectrometry. Along with known yessotoxins (1, 3-6), identified by comparison of their retention times and mass spectra with those of appropriate standards, a new marine toxin, 42,43,44,45,46,47,55-heptanor-41-oxoyessotoxin, 7, was detected. MS/MS experiments were used to gain structural information. 7 represents a new addition to the class of yessotoxins.
The Detection and Identification of 42,43,44,45,46,47,55-Heptonor-41-oxoyessotoxin, a New Marine Toxin from Adriatic Shellfish, by Liquid Chromatography-Mass Spectromery / Ciminiello, Patrizia; Dell'Aversano, Carmela; Fattorusso, Ernesto; Forino, Martino; S., Magno; R., Poletti. - In: CHEMICAL RESEARCH IN TOXICOLOGY. - ISSN 0893-228X. - STAMPA. - 15:(2002), pp. 979-984. [10.1021/tx025527z]
The Detection and Identification of 42,43,44,45,46,47,55-Heptonor-41-oxoyessotoxin, a New Marine Toxin from Adriatic Shellfish, by Liquid Chromatography-Mass Spectromery
CIMINIELLO, PATRIZIA;DELL'AVERSANO, CARMELA;FATTORUSSO, ERNESTO;FORINO, MARTINO;
2002
Abstract
The diarrhetic shellfish toxin composition in the digestive glands of mussels collected in June 2001 from the Northern Adriatic sea was investigated by high performance liquid chromatography coupled with electrospray ion trap mass spectrometry. Along with known yessotoxins (1, 3-6), identified by comparison of their retention times and mass spectra with those of appropriate standards, a new marine toxin, 42,43,44,45,46,47,55-heptanor-41-oxoyessotoxin, 7, was detected. MS/MS experiments were used to gain structural information. 7 represents a new addition to the class of yessotoxins.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
