Purpose: To quantify improvements in adverse in-hospital outcomes between historical and contemporary robot-assisted radical cystectomy (RARC) versus historical and contemporary open RC (ORC). Material and Methods: Within the National Inpatient Sample (2010–2019), RARC and ORC ileal conduit diversion patients were identified. Multivariable logistic and Poisson regression models were fitted. Results: Of RARC patients, 1343 (39%) were historical (2010–2014) and 2087 (61%) were contemporary (2015–2019). Of ORC patients, 5812 (54%) were historical and 5019 (46%) were contemporary. Versus historical counterparts, contemporary RARC patients exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −82% for intraoperative complications to −22% for cumulative postoperative complications. Similarly, versus historical, contemporary ORC patients also exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −72% for intraoperative complications to −12% for median length of stay (LOS). When contemporary RARC was compared to contemporary ORC, RARC adverse in-hospital outcomes were better in 7 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −18% for median LOS. Similarly, when historical RARC was compared to historical ORC, RARC adverse in-hospital outcomes were better in 6 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −15% for median LOS. Conclusion: The magnitude of the improvement in adverse in-hospital outcomes was comparable between contemporary versus historical RARC (nine improved categories) and contemporary versus historical ORC (nine improved categories). However, contemporary RARC outperformed contemporary ORC in 7 of 13 categories of adverse in-hospital outcomes.

Robot‐Assisted Versus Open Radical Cystectomy: Comparison of Adverse In‐Hospital Outcomes / Di Bello, F., Rodriguez Peñaranda, N., Marmiroli, A., Longoni, M., Falkenbach, F., Chi Le, Q., Tian, Z., Goyal, J.A., Collà Ruvolo, C., Califano, G., Creta, M., Saad, F., Shariat, S.F., Puliatti, S., De Cobelli, O., Briganti, A., Graefen, M., Chun, F.H.K., Longo, N., Karakiewicz, P.I.. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 131:8(2025), pp. 1651-1660. [10.1002/jso.28108]

Robot‐Assisted Versus Open Radical Cystectomy: Comparison of Adverse In‐Hospital Outcomes

Di Bello, Francesco;Califano, Gianluigi;Creta, Massimiliano;Longo, Nicola;
2025

Abstract

Purpose: To quantify improvements in adverse in-hospital outcomes between historical and contemporary robot-assisted radical cystectomy (RARC) versus historical and contemporary open RC (ORC). Material and Methods: Within the National Inpatient Sample (2010–2019), RARC and ORC ileal conduit diversion patients were identified. Multivariable logistic and Poisson regression models were fitted. Results: Of RARC patients, 1343 (39%) were historical (2010–2014) and 2087 (61%) were contemporary (2015–2019). Of ORC patients, 5812 (54%) were historical and 5019 (46%) were contemporary. Versus historical counterparts, contemporary RARC patients exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −82% for intraoperative complications to −22% for cumulative postoperative complications. Similarly, versus historical, contemporary ORC patients also exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −72% for intraoperative complications to −12% for median length of stay (LOS). When contemporary RARC was compared to contemporary ORC, RARC adverse in-hospital outcomes were better in 7 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −18% for median LOS. Similarly, when historical RARC was compared to historical ORC, RARC adverse in-hospital outcomes were better in 6 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −15% for median LOS. Conclusion: The magnitude of the improvement in adverse in-hospital outcomes was comparable between contemporary versus historical RARC (nine improved categories) and contemporary versus historical ORC (nine improved categories). However, contemporary RARC outperformed contemporary ORC in 7 of 13 categories of adverse in-hospital outcomes.
2025
Robot‐Assisted Versus Open Radical Cystectomy: Comparison of Adverse In‐Hospital Outcomes / Di Bello, F., Rodriguez Peñaranda, N., Marmiroli, A., Longoni, M., Falkenbach, F., Chi Le, Q., Tian, Z., Goyal, J.A., Collà Ruvolo, C., Califano, G., Creta, M., Saad, F., Shariat, S.F., Puliatti, S., De Cobelli, O., Briganti, A., Graefen, M., Chun, F.H.K., Longo, N., Karakiewicz, P.I.. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 131:8(2025), pp. 1651-1660. [10.1002/jso.28108]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/1013823
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