IRIS
CUBELLIS, MARIA VITTORIA
 Distribuzione geografica
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Continente #
AS - Asia 3.128
NA - Nord America 2.668
EU - Europa 2.239
SA - Sud America 424
AF - Africa 84
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 5
Totale 8.553
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Nazione #
US - Stati Uniti d'America 2.553
SG - Singapore 1.869
RU - Federazione Russa 1.230
CN - Cina 585
BR - Brasile 335
HK - Hong Kong 307
IT - Italia 256
VN - Vietnam 205
DE - Germania 143
FI - Finlandia 115
UA - Ucraina 96
SE - Svezia 79
IE - Irlanda 77
GB - Regno Unito 67
CA - Canada 62
NL - Olanda 46
AR - Argentina 41
CI - Costa d'Avorio 36
FR - Francia 35
MX - Messico 34
IN - India 33
PL - Polonia 28
AT - Austria 22
KR - Corea 19
ZA - Sudafrica 19
BD - Bangladesh 17
JP - Giappone 15
ES - Italia 14
ID - Indonesia 13
TR - Turchia 13
PY - Paraguay 12
CO - Colombia 11
IQ - Iraq 10
EC - Ecuador 9
KE - Kenya 8
VE - Venezuela 7
CL - Cile 6
LT - Lituania 6
PK - Pakistan 6
UZ - Uzbekistan 6
AU - Australia 4
IL - Israele 4
MA - Marocco 4
AE - Emirati Arabi Uniti 3
BE - Belgio 3
CH - Svizzera 3
DK - Danimarca 3
DZ - Algeria 3
EG - Egitto 3
GT - Guatemala 3
KZ - Kazakistan 3
LU - Lussemburgo 3
NP - Nepal 3
PA - Panama 3
RO - Romania 3
TT - Trinidad e Tobago 3
XK - ???statistics.table.value.countryCode.XK??? 3
BN - Brunei Darussalam 2
CG - Congo 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
JM - Giamaica 2
MN - Mongolia 2
OM - Oman 2
PE - Perù 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BF - Burkina Faso 1
BH - Bahrain 1
BO - Bolivia 1
BZ - Belize 1
CW - ???statistics.table.value.countryCode.CW??? 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
EU - Europa 1
GA - Gabon 1
GD - Grenada 1
HN - Honduras 1
HR - Croazia 1
IR - Iran 1
JO - Giordania 1
KG - Kirghizistan 1
KH - Cambogia 1
LB - Libano 1
LV - Lettonia 1
MQ - Martinica 1
MR - Mauritania 1
MT - Malta 1
NA - Namibia 1
NZ - Nuova Zelanda 1
PS - Palestinian Territory 1
PT - Portogallo 1
RW - Ruanda 1
SA - Arabia Saudita 1
SD - Sudan 1
TJ - Tagikistan 1
Totale 8.552
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Città #
Singapore 879
Chandler 317
Moscow 310
Hong Kong 307
Santa Clara 283
Beijing 174
Ashburn 155
Hefei 96
Jacksonville 92
Los Angeles 86
Millbury 84
Princeton 83
Boston 77
Nanjing 63
Ho Chi Minh City 57
New York 57
Munich 45
Napoli 44
Redondo Beach 44
Naples 43
Hanoi 38
Buffalo 35
The Dalles 35
Wilmington 35
Des Moines 33
Ottawa 33
Amsterdam 31
Warsaw 25
São Paulo 24
Mexico City 22
Nanchang 21
Chicago 20
San Jose 20
Dallas 19
Denver 19
Nuremberg 19
Lawrence 18
Orem 18
Seoul 18
Frankfurt am Main 17
Hebei 17
Lappeenranta 16
Seattle 15
Stockholm 15
Woodbridge 15
Ann Arbor 14
Brooklyn 14
Poplar 14
Shenyang 14
Falls Church 13
Norwalk 13
St Petersburg 13
Dong Ket 12
Jiaxing 12
London 12
Montreal 12
Atlanta 11
Helsinki 11
Tokyo 11
Vienna 11
Belo Horizonte 10
Boardman 10
Da Nang 10
Haiphong 10
Kronberg 10
Milan 10
Paris 10
Rome 10
Chennai 9
Falkenstein 9
Manchester 9
San Francisco 9
Dublin 8
Johannesburg 8
Phoenix 8
Tianjin 8
Ankara 7
Berlin 7
Casavatore 7
Fairfield 7
Houston 7
Mumbai 7
Toronto 7
Asunción 6
Brasília 6
Changsha 6
Hải Dương 6
New Delhi 6
Ninh Bình 6
Santo André 6
Tashkent 6
Biên Hòa 5
Guangzhou 5
Nairobi 5
Querétaro 5
Rio de Janeiro 5
Turku 5
Afragola 4
Bexley 4
Caracas 4
Totale 4.348
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Nome #
Ribonucleases and angiogenins from fish. 149
PHYSICO-CHEMICAL CHARACTERZATION OF GEODIN: A NEW B, G- CRYSTALLINE- TYPE PROTEIN SPONGE 147
A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG 127
Pharmacological chaperones: A therapeutic approach for diseases caused by destabilizing missense mutations 120
The Analysis of Variants in the General Population Reveals That PMM2 Is Extremely Tolerant to Missense Mutations and That Diagnosis of PMM2-CDG Can Benefit from the Identification of Modifiers 116
Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19 110
Heterodimerization of Two Pathological Mutants Enhances the Activity of Human Phosphomannomutase2 107
Relaxation of Insulin-like growth factor-2 imprinting and discordant methylation at KvDMR1 in two first-cousins affected by Beckwith-Wiedemann and Klippel-Trenaunay-Weber syndromes 105
Indole-3-glycerol-phosphate Synthase From Sulfolobus-solfataricus As A Model For Studying Thermostable Tim-barrel Enzymes 104
Protective role of a tmprss2 variant on severe covid-19 outcome in young males and elderly women 104
β-Glucose-1,6-Bisphosphate Stabilizes Pathological Phophomannomutase2 Mutants In Vitro and Represents a Lead Compound to Develop Pharmacological Chaperones for the Most Common Disorder of Glycosylation, PMM2-CDG 103
D2A-Ala peptide derived from the urokinase receptor exerts anti-tumoural effects in vitro and in vivo 103
Bioinformatics tools for marine biotechnology: A practical tutorial with a metagenomic approach 102
The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males 101
An intron-less betagamma-crystallin-type gene from the sponge Geodia cydonium. 100
Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones 98
Inherited and Sporadic Epimutations at the IGF2-H19 locus in Beckwith-Wiedemann syndrome and Wilms' tumor. 97
Molecular characterization of G6PD deficiency in Southern Italy: heterogeneity, correlation genotype-phenotype and description of a new variant (G6PD Neapolis). 96
Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease 96
Drug repositioning can accelerate discovery of pharmacological chaperones. 95
The Large Phenotypic Spectrum of Fabry Disease Requires Graduated Diagnosis and Personalized Therapy: A Meta-Analysis Can Help to Differentiate Missense Mutations 95
The Functioning of Sulfolobus-solfataricus Aspartate-aminotransferase 94
Aspartate-aminotransferase From Sulfolobus-solfataricus - A Hyperthermophilic Enzyme 93
Data on the inhibition of cell proliferation and invasion by the D2A-Ala peptide derived from the urokinase receptor 92
Novel genetic variants of KHDC3L and other members of the subcortical maternal complex associated with Beckwith–Wiedemann syndrome or Pseudohypoparathyroidism 1B and multi-locus imprinting disturbances 92
Curcumin Has Beneficial Effects on Lysosomal Alpha-Galactosidase: Potential Implications for the Cure of Fabry Disease 91
Stability of a thermophilic TIM-barrel enzyme: indolglycerol-phosphate synthase from the thermophilic archaeon Sulfolobus solfataricus. 91
Expression of a hyperthermophilic aspartate aminotransferase in Escherichia coli 91
Limited proteolysis as a probe of conformational changes in aspartate aminotransferase from Sulfolobus solfataricus 91
Properties of polyproline II, a secondary structure element implicated in protein-protein interaction 90
IN SILICO DOCKING OF UROKINASE PLASMINOGEN ACTIVATOR AND INTEGRINS 90
Biallelic variant in cyclin B3 is associated with failure of maternal meiosis II and recurrent digynic triploidy 89
D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR 88
In vitro enzyme measurement to test pharmacological chaperone responsiveness in fabry and pompe disease 88
Stability of aspartate aminotransferase from Sulfolobus solfataricus. 87
Identification of trombospondin-1 as a novel amelogenin interactor by functional proteomics 87
A maternal-effect Padi6 variant causes nuclear and cytoplasmic abnormalities in oocytes, as well as failure of epigenetic reprogramming and zygotic genome activation in embryos 86
Looking for protein stabilizing drugs with thermal shift assay. 86
Challenging popular tools for the annotation of genetic variations with a real case, pathogenic mutations of lysosomal alpha-galactosidase 86
Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance 84
Tryptophan Biosynthesis Genes TrpEGC In the Thermoacidophilic Archaebacterium Sulfolobus-solfataricus 82
Environment specific substitution tables for thermophilic proteins 81
Inherited and Sporadic Epimutations at the IGF2-H19 Locus in Beckwith-Wiedemann Syndrome and Wilms’ Tumor. In: Endocrine Involvement in Developmental Syndromes. 81
Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease 81
Drug Repurposing and Lysosomal Storage Disorders: A Trick to Treat 81
Secondary structure assignment that more accurately reflects physical and evolutionary characteristics. 80
An EcoRI polymorphism for the PLAUR gene 80
A Key Molecule Dictating and Regulating Surface Plasmin Formation : The Receptor for Urokinase Plasminogen ActivatorSerine Proteases and Their Serpin Inhibitors in the Nervous System 80
Comparative studies on thermophilicity and thermostability of aspartate aminotransferases. 80
Stability of aspartate aminotransferase from Sulfolobus solfataricus 79
ReBaTSA: A simplified CeTSA protocol for studying recombinant mutant proteins in bacterial extracts 78
PEGYLATION, THE ULTIMATE STRATEGY TO IMPROVE THE IN VIVO EFFICIENCY OF BIOACTIVE COMPOUNDS 78
Identification of a novel mutation in the myosin VIIA motor domain in a family with autosomal dominant hearing loss (DFNA11). 77
Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder. 77
Mechanistic Insight into the Mode of Action of Acid β-Glucosidase Enhancer Ambroxol 77
The active site of Sulfolobus solfataricus aspartate aminotransferase 76
Autocrine saturation of pro-urokinase receptors on human A431 cells. 75
Passenger mutations as a target for the personalized therapy of cancer 74
An open reading frame in intron seven of the sea urchin DNA-methyltransferase gene codes for a functional AP1 endonuclease. 74
Different Mechanisms Cause Imprinting defects at the IGF2/H19 locus in Beckwith-Wiedemann Syndrome and Wilms’ Tumour. 74
(Epi)genotype-phenotype correlations in Beckwith-Wiedemann syndrome. 73
An extremely thermostable aromatic aminotransferase from the hyperthermophilic archaeon Pyrococcus furiosus. 72
Use of fast protein liquid chromatography (FPLC) for the purification of synthetic oligonucleotides 71
The pharmacological chaperone 1-deoxynojirimycin increases the activity and lysosomal trafficking of multiple mutant forms of acid alpha-glucosidase 69
An intron-less βγ-crystallin-type gene from the sponge Geodia cydonium 69
Frequent pathological human mutations: a survey. 68
Exploring ligand interactions with human phosphomannomutases using recombinant bacterial thermal shift assay and biochemical validation 67
Assessment of gene variant amenability for pharmacological chaperone therapy with 1-deoxygalactonojirimycin in fabry disease 67
Enzymes from extreme thermophilic bacteria as special catalysts: studies on a beta -galactosidase from Sulfolobus solfataricus 66
Biochemical phenotype of a common disease-causing mutation and a possible therapeutic approach for the phosphomannomutase 2-associated disorder of glycosylation 66
Use of fast protein liquid chromatography for the purification of synthetic oligonucleotides 65
Gain of function in CDKN1C 64
Fabry_CEP: a tool to identify Fabry mutations responsive to pharmacological chaperones. 63
An ORF in the intron seven of the sea urchin DNA-methyltransferase gene codes for a functional AP1 endonuclease 62
The receptor for urokinase-plasminogen activator 62
The KCNQ1OT1 Imprinting Control Region and non-coding RNA: new properties derived from the study of Beckwith-Wiedemann syndrome and Silver-Russell syndrome cases. 61
Relaxation of Insulin-like Growth Factor 2 Imprinting and Discordant Methylation at KvDMR1 in Two First Cousins Affected by Beckwith-Wiedemann and Klippel-Trenaunay-Weber Syndromes 61
Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor. 58
Binding of single-chain prourokinase to the urokinase receptor of human U937 cells. 57
Antitumor Action of Seminal Ribonuclease, Its Dimeric Structure, and Its Resistance to the Cytosolic Ribonuclease Inhibitor† 56
A thermodynamic assay to test pharmacological chaperones for Fabry disease. 56
Fetal growth patterns in Beckwith-Wiedemann syndrome 56
Nucleotide sequence of a cDNA coding for bovine mitochondrial aspartate aminotransferase. 55
Silver-Russell syndrome- and Beckwith-Wiedemann syndrome- phenotypes associated with 11p duplication in a single family. 55
Polyproline II in protein interactions 55
The urokinase receptor and regulation of cell surface plasminogen activation 55
Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. 55
Prediction of the responsiveness to pharmacological chaperones: lysosomal human alpha-galactosidase, a case of study 54
Bioinformatics-Driven Multi-Factorial Insight into α-Galactosidase Mutations 53
Hypomethylation at multiple maternally methylated imprinted regions including PLAGL1 and GNAS loci in Beckwith-Wiedemann syndrome. 53
Beneficial effects of Glc-1,6-P2 modulation on mutant phosphomannomutase-2 52
The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF binding sites 52
Identification of a novel mutation in the myosin VIIA motor domain in a family with autosomal dominant hearing loss (DFNA11). 51
Use of Fast Protein Liquid-chromatography For the Purification of Synthetic Oligonucleotides 51
Preparation and characterization of geodin. A betagamma-crystallin-type protein from a sponge. 50
Characterization of aromatic aminotransferases from the hyperthermophilic archaeon Thermococcus litoralis. 50
Isolation and sequencing of a new β-galactosidase-encoding archaebacterial gene 49
Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. 49
Cloning and sequencing of the gene coding for aspartate aminotransferase from the thermoacidophilic archaebacterium Sulfolobus solfataricus 49
Taming molecular flexibility to tackle rare diseases. 49
Totale 7.882
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Categoria #
all - tutte 30.915
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.915
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021109 0 0 0 0 0 0 20 5 28 6 28 22
2021/2022503 16 0 12 2 5 9 8 16 78 35 80 242
2022/2023677 108 97 18 45 84 81 13 60 108 23 31 9
2023/2024392 27 77 36 15 22 12 3 48 10 10 96 36
2024/20253.031 200 208 12 32 125 192 343 163 208 306 954 288
2025/20263.244 573 388 472 541 961 294 15 0 0 0 0 0
Totale 8.737