NICOSIA, Alfredo

NICOSIA, Alfredo  

DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE  

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Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques. 1.1 Articolo in rivista 2012 Rosario, M; Borthwick, N; Stewart Jones, Gb; Mbewe Mvula, A; Bridgeman, A; Colloca, S; Montefiori, D; Mcmichael, Aj; Nicosia, Alfredo; Quakkelaar, Ed; Drijfhout, Jw; Melief, Cj; Hanke, T.
Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults. 1.1 Articolo in rivista 2013 Ogwang, C; Afolabi, M; Kimani, D; Jagne, Yj; Sheehy, Sh; Bliss, Cm; Duncan, Cj; Collins, Ka; Garcia Knight, Ma; Kimani, E; Anagnostou, Na; Berrie, E; Moyle, S; Gilbert, Sc; Spencer, Aj; Soipei, P; Mueller, J; Okebe, J; Colloca, S; Cortese, R; Viebig, Nk; Roberts, R; Gantlett, K; Lawrie, Am; Nicosia, Alfredo; Imoukhuede, Eb; Bejon, P; Urban, Bc; Flanagan, Kl; Ewer, Kj; Chilengi, R; Hill, Av; Bojang, K.
Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials. 1.1 Articolo in rivista 2013 Capone, S; D'Alise, Am; Ammendola, V; Colloca, S; Cortese, R; Nicosia, Alfredo; Folgori, A.
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. 1.1 Articolo in rivista 2012 Sheehy, Sh; Duncan, Cj; Elias, Sc; Choudhary, P; Biswas, S; Halstead, Fd; Collins, Ka; Edwards, Nj; Douglas, Ad; Anagnostou, Na; Ewer, Kj; Havelock, T; Mahungu, T; Bliss, Cm; Miura, K; Poulton, Id; Lillie, Pj; Antrobus, Rd; Berrie, E; Moyle, S; Gantlett, K; Colloca, S; Cortese, R; Long, Ca; Sinden, Re; Gilbert, Sc; Lawrie, Am; Doherty, T; Faust, Sn; Nicosia, Alfredo; Hill, Av; Draper, Sj
Hepatitis C virus-multispecific T-cell responses without viremia or seroconversion among Egyptian health care workers at high risk of infection. 1.1 Articolo in rivista 2012 Abdelwahab, Sf; Zakaria, Z; Sobhy, M; Rewisha, E; Mahmoud, Ma; Amer, Ma; Del Sorbo, M; Capone, S; Nicosia, Alfredo; Folgori, A; Hashem, M; El Kamary, Ss
Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector. 1.1 Articolo in rivista 2012 O'Hara, Ga; Duncan, Cj; Ewer, Kj; Collins, Ka; Elias, Sc; Halstead, Fd; Goodman, Al; Edwards, Nj; Reyes Sandoval, A; Bird, P; Rowland, R; Sheehy, Sh; Poulton, Id; Hutchings, C; Todryk, S; Andrews, L; Folgori, A; Berrie, E; Moyle, S; Nicosia, Alfredo; Colloca, S; Cortese, R; Siani, L; Lawrie, Am; Gilbert, Sc; Hill, Av
Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors. 1.1 Articolo in rivista 2012 Sheehy, Sh; Duncan, Cj; Elias, Sc; Biswas, S; Collins, Ka; O'Hara, Ga; Halstead, Fd; Ewer, Kj; Mahungu, T; Spencer, Aj; Miura, K; Poulton, Id; Dicks, Md; Edwards, Nj; Berrie, E; Moyle, S; Colloca, S; Cortese, R; Gantlett, K; Long, Ca; Lawrie, Am; Gilbert, Sc; Doherty, T; Nicosia, Alfredo; Hill, Av; Draper, Sj
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus. 1.1 Articolo in rivista 2014 Prentoe, J; Serre, Sb; Ramirez, S; Nicosia, Alfredo; Gottwein, Jm; Bukh, J.
Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice. 1.1 Articolo in rivista 2013 Ondondo, B; Brennan, C; Nicosia, Alfredo; Crome, Sj; Hanke, T.
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization. 1.1 Articolo in rivista 2013 Quinn, Km; Da Costa, A; Yamamoto, A; Berry, D; Lindsay, Rw; Darrah, Pa; Wang, L; Cheng, C; Kong, Wp; Gall, Jg; Nicosia, Alfredo; Folgori, A; Colloca, S; Cortese, R; Gostick, E; Price, Da; Gomez, Ce; Esteban, M; Wyatt, Ls; Moss, B; Morgan, C; Roederer, M; Bailer, Rt; Nabel, Gj; Koup, Ra; Seder, Ra
Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine. 1.1 Articolo in rivista 2012 Knudsen, Ml; Mbewe Mvula, A; Rosario, M; Johansson, Dx; Kakoulidou, M; Bridgeman, A; Reyes Sandoval, A; Nicosia, Alfredo; Ljungberg, K; Hanke, T; Liljestr?m, P.
Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice. 1.1 Articolo in rivista 2012 Lacek, K; Vercauteren, K; Grzyb, K; Naddeo, M; Verhoye, L; S?owikowski, Mp; Fafi Kremer, S; Patel, Ah; Baumert, Tf; Folgori, A; Leroux Roels, G; Cortese, R; Meuleman, P; Nicosia, Alfredo
Successful vaccination induces multifunctional memory T-cell precursors associated with early control of hepatitis C virus. 1.1 Articolo in rivista 2012 Park, Sh; Shin, Ec; Capone, S; Caggiari, L; De Re, V; Nicosia, Alfredo; Folgori, A; Rehermann, B.
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation. 1.1 Articolo in rivista 2013 Ewer, Kj; O'Hara, Ga; Duncan, Cj; Collins, Ka; Sheehy, Sh; Reyes Sandoval, A; Goodman, Al; Edwards, Nj; Elias, Sc; Halstead, Fd; Longley, Rj; Rowland, R; Poulton, Id; Draper, Sj; Blagborough, Am; Berrie, E; Moyle, S; Williams, N; Siani, L; Folgori, A; Colloca, S; Sinden, Re; Lawrie, Am; Cortese, R; Gilbert, Sc; Nicosia, Alfredo; Hill, Av
Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1. 1.1 Articolo in rivista 2014 Borthwick, N; Ahmed, T; Ondondo, B; Hayes, P; Rose, A; Ebrahimsa, U; Hayton, Ej; Black, A; Bridgeman, A; Rosario, M; Hill, Av; Berrie, E; Moyle, S; Frahm, N; Cox, J; Colloca, S; Nicosia, Alfredo; Gilmour, J; Mcmichael, Aj; Dorrell, L; Hanke, T.
Vaccination to conserved influenza antigens in mice using a novel Simian adenovirus vector, PanAd3, derived from the bonobo Pan paniscus. 1.1 Articolo in rivista 2013 Vitelli, A; Quirion, Mr; Lo, Cy; Misplon, Ja; Grabowska, Ak; Pierantoni, A; Ammendola, V; Price, Ge; Soboleski, Mr; Cortese, R; Colloca, S; Nicosia, Alfredo; Epstein, Sl
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein 1.1 Articolo in rivista 2007 Catanese, M. T.; Graziani, R.; von Hahn, T.; Moreau, M; Huby, T; Paonessa, G; Santini, C; Luzzago, A; Rice, Cm; Cortese, R; Vitelli, A; Nicosia, Alfredo
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants. 1.1 Articolo in rivista 2010 Catanese, Mt; Ansuini, H; Graziani, R; Huby, T; Moreau, M; Ball, Jk; Paonessa, G; Rice, Cm; Cortese, R; Vitelli, A; Nicosia, Alfredo
Novel Adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man 1.1 Articolo in rivista 2012 E., Barnes; A., Folgori; S., Capone; L., Swadling; S., Aston; A., Kurioka; J., Meyer; R., Huddart; K., Smith; R., Townsend; A., Brown; R., Antrobus; V., Ammendola; M., Naddeo; G., O’Hara; C., Willberg; A., Harrison; F., Grazioli; M. L., Esposito; L., Siani; C., Traboni; Y., Oo; D., Adams; A., Hill; S., Colloca; Nicosia, Alfredo; R., Cortese; P., Klenerman
Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines. 1.1 Articolo in rivista 2010 Draper, Sj; Biswas, S; Spencer, Aj; Remarque, Ej; Capone, S; Naddeo, M; Dicks, Md; Faber, Bw; de Cassan, Sc; Folgori, A; Nicosia, Alfredo; Gilbert, Sc; Hill, Av