Nome |
# |
Nutraceuticals: A paradigm of proactive medicine, file e268a732-a0b6-4c8f-e053-1705fe0a812c
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515
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Antioxidant peptides from “Mozzarella di Bufala Campana DOP” after simulated gastrointestinal digestion: In vitro intestinal protection, bioavailability, and anti-haemolytic capacity, file e268a72e-9b9d-4c8f-e053-1705fe0a812c
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286
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5'-C-ethyl-tetrazolyl-N 6-substituted adenosine and 2-chloro-adenosine derivatives as highly potent dual acting A1 adenosine receptor agonists and A3 adenosine receptor antagonists, file e268a72d-1a8a-4c8f-e053-1705fe0a812c
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279
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Simulated gastrointestinal digestion, intestinal permeation and plasma protein interaction of white, green, and black tea polyphenols, file e268a72e-9baa-4c8f-e053-1705fe0a812c
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244
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Antioxidant and antimicrobial properties of traditional green and purple "Napoletano" basil cultivars (Ocimum basilicum L.) from Campania region (Italy), file e268a72e-9b2c-4c8f-e053-1705fe0a812c
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218
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Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: A critical review of in vitro and in vivo animal-based studies, file e268a730-8507-4c8f-e053-1705fe0a812c
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189
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Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors, file e268a72f-21a8-4c8f-e053-1705fe0a812c
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165
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Nutraceuticals in hypercholesterolaemia: an overview, file e268a732-af19-4c8f-e053-1705fe0a812c
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153
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An efficient synthesis of 1-arylindazole-3-carboxamides using nitrile imines, isocyanides and 2-hydroxymethylbenzoic acid, followed by a chemoselective Buchwald–Hartwig intramolecular cyclization, file e268a72e-acc2-4c8f-e053-1705fe0a812c
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130
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Toxicity of aflatoxin B1 towards the vitamin D receptor (VDR), file e268a72d-2495-4c8f-e053-1705fe0a812c
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125
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Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis, file e268a732-2b3e-4c8f-e053-1705fe0a812c
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118
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Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer, file e268a72f-23db-4c8f-e053-1705fe0a812c
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116
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A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist., file e268a72f-336d-4c8f-e053-1705fe0a812c
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107
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N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor., file e268a72c-c80b-4c8f-e053-1705fe0a812c
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98
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Investigation on side-product formation during the synthesis of a lactoferrin-derived lactam-bridged cyclic peptide, file e268a72f-c854-4c8f-e053-1705fe0a812c
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88
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Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation, file e268a72f-f115-4c8f-e053-1705fe0a812c
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87
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Induction of hair keratins expression by an Annurca Apple-based nutraceutical formulation in human follicular cells, file e268a731-ac7a-4c8f-e053-1705fe0a812c
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86
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Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity, file e268a72f-30fa-4c8f-e053-1705fe0a812c
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73
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Novel temporin L antimicrobial peptides: promoting self-assembling by lipidic tags to tackle superbugs, file e268a732-11c8-4c8f-e053-1705fe0a812c
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72
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Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds, file e268a732-f47a-4c8f-e053-1705fe0a812c
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64
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Biophysical and biochemical characterization of a liposarcoma-derived recombinant MnSOD protein acting as an anticancer agent, file e268a72e-8827-4c8f-e053-1705fe0a812c
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62
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A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells, file e268a72f-f3e4-4c8f-e053-1705fe0a812c
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61
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Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist, file e268a72f-2d89-4c8f-e053-1705fe0a812c
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60
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Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis, file e268a72d-df71-4c8f-e053-1705fe0a812c
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58
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Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and Bioassays, file e268a72d-5763-4c8f-e053-1705fe0a812c
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53
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Exploiting the indole scaffold to design compounds binding to different pharmacological targets, file e268a731-bd9c-4c8f-e053-1705fe0a812c
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51
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Regulation of HuR structure and function by dihydrotanshinone-I, file e268a72f-263d-4c8f-e053-1705fe0a812c
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44
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Genotoxicity assessment of three nutraceuticals containing natural antioxidants extracted from agri-food waste biomasses, file e268a731-fa0a-4c8f-e053-1705fe0a812c
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44
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Urotensin-II Receptor: A Double Identity Receptor Involved in Vasoconstriction and in the Development of Digestive Tract Cancers and other Tumors, file e268a72e-6f04-4c8f-e053-1705fe0a812c
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43
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Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer, file e268a72f-23d5-4c8f-e053-1705fe0a812c
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32
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Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction, file e268a730-7010-4c8f-e053-1705fe0a812c
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32
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WNT inhibitory activity of malus pumila miller cv annurca and malus domestica cv limoncella apple extracts on human colon-rectal cells carrying familial adenomatous polyposis mutations, file e268a72f-1b0d-4c8f-e053-1705fe0a812c
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30
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Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells, file e268a72e-b058-4c8f-e053-1705fe0a812c
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28
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New Anticancer Agents Mimicking Protein Recognition Motifs., file e268a72c-d53c-4c8f-e053-1705fe0a812c
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26
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Canned bluefin tuna, an in vitro cardioprotective functional food potentially safer than commercial fish oil based pharmaceutical formulations, file e268a72e-9bea-4c8f-e053-1705fe0a812c
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26
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Investigation of the stereochemical-dependent DNA and RNA binding of arginine-based nucleopeptides, file e268a732-0164-4c8f-e053-1705fe0a812c
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23
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Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors, file e268a730-0f6f-4c8f-e053-1705fe0a812c
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20
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Correlation between work impairment, scores of rhinitis severity and asthma using the MASK-air® App, file e268a732-9251-4c8f-e053-1705fe0a812c
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19
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Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops, file e268a72f-cbe9-4c8f-e053-1705fe0a812c
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18
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Design and pharmacological evaluation of Ibuprofen amides derivatives as dual FAAH/COX inhibitors, file e268a731-d29b-4c8f-e053-1705fe0a812c
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17
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Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand, file ae557be3-fa3e-40ff-8130-c5305d427828
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16
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Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode, file e268a72c-f80c-4c8f-e053-1705fe0a812c
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13
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Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation, file e268a72f-f3e2-4c8f-e053-1705fe0a812c
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13
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Sampling protein motion and solvent effect during ligand binding., file e268a72d-5698-4c8f-e053-1705fe0a812c
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12
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Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors, file e268a733-2628-4c8f-e053-1705fe0a812c
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11
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Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells, file e268a731-b8a6-4c8f-e053-1705fe0a812c
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10
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Intestinal anti-inflammatory effect of a peptide derived from gastrointestinal digestion of buffalo (Bubalus bubalis) mozzarella cheese, file e268a732-c7e9-4c8f-e053-1705fe0a812c
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10
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Colon Bioaccessibility and Antioxidant Activity of White, Green and Black Tea Polyphenols Extract after In Vitro Simulated Gastrointestinal Digestion, file e268a732-d464-4c8f-e053-1705fe0a812c
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10
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Synthesis of new isoxazole derivatives as fxr agonists with improved pharmacokinetic properties, file e268a733-6ae2-4c8f-e053-1705fe0a812c
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10
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CALLI VEGETALI DA BUCCIA DI MELA E LORO COLTURA PER LA PRODUZIONE DEI FITOCOMPOSTI FLORIZINA ED ACIDO URSOLICO, file 913a9282-5f5c-43fb-abc8-ed80ae38a574
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8
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Combining 4-Aminoquinoline- and Clotrimazole-Based Pharmacophores toward Innovative and Potent Hybrid Antimalarials., file e268a72c-d236-4c8f-e053-1705fe0a812c
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8
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Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue, file e268a72f-1992-4c8f-e053-1705fe0a812c
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8
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Breast tumor cell invasion and pro-invasive activity of cancer-associated fibroblasts co-targeted by novel urokinase-derived decapeptides, file e268a732-16f0-4c8f-e053-1705fe0a812c
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8
|
Use of yeast extract to elicit a pulp-derived callus cultures from Annurca apple and potentiate its biological activity, file 2d4bc21a-4c1d-428f-a0e0-4863884693be
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5
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Antiviral activity of Taurisolo® during bovine alphaherpesvirus 1 infection, file 4083ead8-0729-4afc-87f7-2e3e625b5639
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5
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The economic impact of biosimilars in Italy: a scenario analysis, file e268a731-7441-4c8f-e053-1705fe0a812c
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5
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Combined HAT/EZH2 modulation leads to cancer-selective cell death, file e268a732-5cea-4c8f-e053-1705fe0a812c
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5
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The Effects of a Cinchona Supplementation on Satiety, Weight Loss and Body Composition in a Population of Overweight/Obese Adults: A Controlled Randomized Study, file d5536256-0977-485d-bb00-ef298f05f043
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4
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ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice, file e268a732-a099-4c8f-e053-1705fe0a812c
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4
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May Polyphenols Have a Role Against Coronavirus Infection? An Overview of in vitro Evidence, file e268a732-eba2-4c8f-e053-1705fe0a812c
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4
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Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques, file e268a72d-7591-4c8f-e053-1705fe0a812c
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3
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Novel propanamides as fatty acid amide hydrolase inhibitors, file e268a72e-8aff-4c8f-e053-1705fe0a812c
|
3
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Promelanogenic Effects by an Annurca Apple-Based Natural Formulation in Human Primary Melanocytes, file e268a732-c5e8-4c8f-e053-1705fe0a812c
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3
|
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury, file e268a732-e690-4c8f-e053-1705fe0a812c
|
3
|
Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence, file 5eb7805c-59a3-43dc-84bc-4f261aa30797
|
2
|
Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands, file e268a72d-4dd4-4c8f-e053-1705fe0a812c
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2
|
New insights into the interaction between pyrrolyl diketoacids and HIV-1 integrase active site and comparison with RNase H, file e268a72f-2bae-4c8f-e053-1705fe0a812c
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2
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α-Amino acids as synthons in the Ugi-5-centers-4-components reaction: Chemistry and applications, file e268a730-bfdc-4c8f-e053-1705fe0a812c
|
2
|
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells, file e268a732-e57f-4c8f-e053-1705fe0a812c
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2
|
Biomimetic materials and bioadhesionBlue4Glue, file e268a72c-d9f0-4c8f-e053-1705fe0a812c
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1
|
A unique capsular polysaccharide structure from the psy-chrophilic marine bacterium Colwellia psychrerythraea 34H that mimicks antifreeze (glyco) proteins, file e268a72c-f3e0-4c8f-e053-1705fe0a812c
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1
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(1S,3R,4S,5R)5-O-Caffeoylquinic acid: isolation, stereo-structure characterization and biological activity, file e268a72d-9b98-4c8f-e053-1705fe0a812c
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1
|
Bioassay-guided identification of the antihyperglycaemic constituents of walnut (Juglans regia) leaves, file e268a72d-a61a-4c8f-e053-1705fe0a812c
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1
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A Practical Synthesis of 5-Aroyl-1-aryltetrazoles Using an Ugi-Like 4-Component Reaction Followed by a Biomimetic Transamination, file e268a72e-a5b4-4c8f-e053-1705fe0a812c
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1
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Multicomponent Reaction of Z-Chlorooximes, Isocyanides, and Hydroxylamines as Hypernucleophilic Traps. A One-Pot Route to Aminodioximes and Their Transformation into 5-Amino-1,2,4-oxadiazoles by Mitsunobu-Beckmann Rearrangement, file e268a72e-a67b-4c8f-e053-1705fe0a812c
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1
|
To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis, file e268a72e-ab9f-4c8f-e053-1705fe0a812c
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1
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Nitrile N-Oxides and Nitrile Imines as New Fuels for the Discovery of Novel Isocyanide-Based Multicomponent Reactions, file e268a72e-ac4e-4c8f-e053-1705fe0a812c
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1
|
Synthesis of aminocarbonyl N-acylhydrazones by a three-component reaction of isocyanides, hydrazonoyl chlorides, and carboxylic acids, file e268a72e-ad16-4c8f-e053-1705fe0a812c
|
1
|
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from fragment Virtual Screening, file e268a72e-ae3d-4c8f-e053-1705fe0a812c
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1
|
N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase, file e268a72f-2456-4c8f-e053-1705fe0a812c
|
1
|
Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma, file e268a72f-26bb-4c8f-e053-1705fe0a812c
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1
|
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3, file e268a72f-2d8c-4c8f-e053-1705fe0a812c
|
1
|
Urokinase receptor derived peptides as potent inhibitors of the formyl peptide receptor type 1-triggered cell migration, file e268a72f-3e9b-4c8f-e053-1705fe0a812c
|
1
|
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors, file e268a72f-6d5d-4c8f-e053-1705fe0a812c
|
1
|
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts, file e268a730-05d1-4c8f-e053-1705fe0a812c
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1
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Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases, file e268a730-05d8-4c8f-e053-1705fe0a812c
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1
|
Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators, file e268a730-7add-4c8f-e053-1705fe0a812c
|
1
|
Continuous Flow Synthesis of Thieno[2,3-c]isoquinolin-5(4H)-one Scaffold: A Valuable Source of PARP-1 Inhibitors, file e268a730-7b44-4c8f-e053-1705fe0a812c
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1
|
Online comprehensive hydrophilic interaction chromatography × reversed phase liquid chromatography coupled to mass spectrometry for in depth peptidomic profile of microalgae gastro-intestinal digests, file e268a730-d90e-4c8f-e053-1705fe0a812c
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1
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Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes, file e268a731-382d-4c8f-e053-1705fe0a812c
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1
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Totale |
4.172 |