WHO global research priorities for antimicrobial resistance in human health

Bertagnolio, Silvia; Dobreva, Zlatina; Centner, Chad M; Olaru, Ioana Diana; Donà, Daniele; Burzo, Stefano; Huttner, Benedikt D; Chaillon, Antoine; Gebreselassie, Nebiat; Teodora, Wi; Hasso-Agopsowicz, Mateusz; Allegranzi, Benedetta; Sati, Hatim; Ivanovska, Verica; Kothari, Kavita U; Balkhy, Hanan H; Cassini, Alessandro; Hamers, Raph L; Weezenbeek,; Kitty Van Weezenbeek,; Who Research Agenda For Amr In Human Health Collaborators: David Aanensen 12,; Alexandre Alanio 13,; Ana Alastruey-Izquierdo 14,; Tinsae Alemayehu 15,; Majdi Al-Hasan 16,; Karel Allegaert 17,; Amal Saif Al-Maani 18,; Jameela Al-Salman 19,; Abeer Nizar Alshukairi 20,; Afreenish Amir 21,; Tanya Applegate 22,; George, F Araj 23; Marlen Arce Villalobos 24,; Christine Årdal 25,; Diane Ashiru-Oredope 26,; Elizabeth, A Ashley 27; François-Xavier Babin 28,; Laura, H Bachmann 29; Till Bachmann 30,; Kate Susan Baker 31,; Manica Balasegaram 32,; Colleen Bamford 33,; Fernando Baquero 34,; Laura Isabel Barcelona 35,; Quique Bassat 36,; Matteo Bassetti 37,; Sulagna Basu 38,; Justin Beardsley 39,; Grey Benoit Vásquez 40,; James, A Berkley 41; Anuj, K Bhatnagar 42; Julia Bielicki 43,; Julie Bines 44,; Felix Bongomin 45,; Robert, A Bonomo 46; John, S Bradley 47; Catriona Bradshaw 48,; Ana Brett 49,; Adrian Brink 50,; Colin Brown 26,; Jeremy Brown 51,; Kirsty Buising 52,; Carolee Carson 53,; Anna Cristina Carvalho 54,; Elio Castagnola 55,; Marco Cavaleri 56,; Michele Cecchini 57,; Chishala Chabala 58,; Richard, E Chaisson 59; Arunaloke Chakrabarti 60,; Clare Chandler 61,; Sujith John Chandy 62,; Esmita Charani 63,; Lisa Chen 64,; Francesca Chiara 65,; Anuradha Chowdhary 66,; Arlene Chua 67,; Pem Chuki 68,; Doo Ryeon Chun 69,; Gavin Churchyard 70,; Daniela Cirillo 71,; Lauren Clack 72,; Susan, E Coffin 73; Jennifer Cohn 32,; Michelle Cole 74,; John Conly 75,; Ben Cooper 12,; Alejandra Corso 76,; Sara, E Cosgrove 77; Helen Cox 78,; Charles, L Daley 79; Saffiatou Darboe 80,; Tom Darton 81,; Gerry Davies 82,; Viviana De Egea 83,; Amela Dedeić-Ljubović 84,; Miranda Deeves 85,; Claudia Denkinger 86,; Jo-Anne, R Dillon 87; Angela Dramowski 88,; Brian Eley 89,; Susanna Maria Roberta Esposito 90,; Sabiha, Y Essack 91; Helmia Farida 92,; Joveria Farooqi 93,; Nicholas Feasey 94,; Cecilia Ferreyra 95,; Helen Fifer 26,; Heather Finlayson 88,; Mike Frick 96,; Ana Cristina Gales 97,; Luisa Galli 98,; Sumanth Gandra 99,; Jeffrey, S Gerber 100; Christian Giske 101,; Bruce Gordon 85,; Nelesh Govender 102,; Nathalie Guessennd 103,; Ibrehima Guindo 104,; Elmira Gurbanova 105,; Amanda Gwee 106,; Ferry Hagen 107,; Stephan Harbarth 108,; John Haze 109,; Jutta Heim 110,; Rene Hendriksen 111,; Robert Simon Heyderman 112,; Kathryn Elizabeth Holt 61,; Martin Hönigl 113,; Edward, W Hook 114; William Hope 82,; Heidi Hopkins 61,; Gwenda Hughes 61,; Ghada Ismail 115,; Mohammad Iqbal Issack 116,; Jan Jacobs 117,; Dušan Jasovský 118,; Fyeza Jehan 119,; Antonieta Jimenez Pearson 120,; Makoto Jones 121,; Mohan, P Joshi 122; Arti Kapil 123,; Samuel Kariuki 124,; Abhilasha Karkey 125,; Gregory, L Kearns 126; Karen Helena Keddy 127,; Nina Khanna 128,; Akiko Kitamura 129,; Kaija-Leena Kolho 130,; Dimitrios, P Kontoyiannis 131; Anita Kotwani 132,; Roman, S Kozlov 133; Katharina Kranzer 61,; Ranmini Kularatne 134,; Monica, M Lahra 135; Bradley, J Langford 136; Rafael Laniado-Laborin 137,; Joakim Larsson 138,; Cornelia Lass-Flörl 139,; Kirsty Le Doare 140,; Hyukmin Lee 141,; Fernanda Lessa 29,; Anna, S Levin 142; Direk Limmathurotsakul 143,; Nilton Lincopan 144,; Lo Vecchio, Andrea; Rakesh Lodha 146,; Mark Loeb 147,; Yves Longtin 148,; David Chien Lye 149,; Asif Mujtaba Mahmud 150,; Célia Manaia 151,; Lenore Manderson 152,; Ivana Mareković 153,; Kalisvar Marimuthu 154,; Irene Martin 155,; Tapfumanei Mashe 156,; Zeng Mei 157,; Jacques, F Meis 158; Flávio Augusto Lyra Tavares De Melo 159,; Marc Mendelson 50,; Angelica Espinosa Miranda 160,; David Moore 161,; Chantal Morel 162,; Nyambura Moremi 163,; Maria Luisa Moro 164,; Francis Moussy 85,; Stephen Mshana 165,; Arno Mueller 85,; Francis, J Ndow 166; Mark Nicol 167,; Andrew Nunn 168,; Stephen Obaro 169,; Christina, W Obiero 170; Iruka, N Okeke 171; Uduak Okomo 172,; Tochi, J Okwor 173; Rita Oladele 174,; Sylvia Omulo 175,; Pascale Ondoa 176,; Juana Medarda Ortellado De Canese 177,; Luis Ostrosky-Zeichner 178,; Maria Clara Padoveze 179,; Madhukar Pai 180,; Benjamin Park 29,; Julian Parkhill 181,; Christopher, M Parry 182; Rosanna Peeling 61,; Luísa Maria Sobreira Vieira Peixe 183,; Olga Perovic 184,; Melinda, M Pettigrew 185; Nicola Principi 186,; Céline Pulcini 187,; Nelly Puspandari 188,; Timothy Rawson 63,; Denasha Lavanya Reddy 152,; Kessendri Reddy 152,; Paulo Redner 189,; Juan Luis Rodríguez Tudela 190,; Jesús Rodríguez-Baño 191,; Susan Rogers Van Katwyk 192,; Emmanuel Roilides 193,; Christine Rollier 194,; Leslie Rollock 195,; Jean-Baptiste Ronat 196,; Etienne Ruppe 197,; Manish Sadarangani 198,; David Salisbury 199,; Mounerou Salou 200,; Luc Hervé Samison 201,; Maurizio Sanguinetti 202,; Massimo Sartelli 203,; Natalie Schellack 204,; Jeroen Schouten 205,; Mitchell, J Schwaber 206; Jeremiah Seni 207,; Abiola Senok 208,; William, M Shafer 209; Sadia Shakoor 210,; Donald Sheppard 53,; Jong-Hee Shin 211,; Sonia Sia 212,; Dawn Sievert 29,; Ishwar Singh 213,; Rupak Singla 214,; Robert Leo Skov 215,; Olusegun, O Soge 216; Rosanne Sprute 217,; Arjun Srinivasan 218,; Subasree Srinivasan 29,; Arnfinn Sundsfjord 219,; Evelina Tacconelli 220,; Sabira Tahseen 221,; Viroj Tangcharoensathien 222,; Thomas Tängdén 223,; Karin Thursky 224,; Guy Thwaites 225,; Renata Tigulini De Souza Peral 226,; Deborah Tong 85,; Hafsah Deepa Tootla 227,; Constantinos Tsioutis 228,; Katy, M Turner 229; Paul Turner 229,; Shaheed Vally Omar 230,; Wendy Wj Van De Sande 231,; Susan Van Den Hof 232,; Rogier Van Doorn 233,; Balaji Veeraraghavan 234,; Paul Verweij 235,; Retno Wahyuningsih 236,; Hui Wang 237,; Adilia Warris 238,; Hillard Weinstock 239,; Evelyn Wesangula 240,; David Whiley 218,; Peter, J White 241; Phoebe Williams 242,; Yonghong Xiao 243,; Martin Yagui Moscoso 244,; Hsu Li Yang 245,; Sachiyo Yoshida 85,; Yunsong Yu 246,; Żabick, Dorota; Zignol, Matteo

doi:10.1016/S2666-5247(24)00134-4

: The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treatment of antimicrobial-resistant infections, in addition to addressing the overarching knowledge gaps in AMR epidemiology, burden and drivers, policies and regulations, and awareness and education. The research priorities were identified through a multistage process, starting with a comprehensive scoping review of knowledge gaps, with expert inputs gathered through a survey and open call. The priority setting involved a rigorous modified Child Health and Nutrition Research Initiative approach, ensuring global representation and applicability of the findings. The ultimate goal of this research agenda is to encourage research and investment in the generation of evidence to better understand AMR dynamics and facilitate policy translation for reducing the burden and consequences of AMR.

WHO global research priorities for antimicrobial resistance in human health / Silvia, B., Zlatina, D., Chad M, C., Ioana Diana, O., Daniele, D., Stefano, B., Benedikt D, H., Antoine, C., Nebiat, G., Teodora, W.i., Mateusz, H., Benedetta, A., Hatim, S., Verica, I., Kavita U, K., Hanan H, B., Alessandro, C., Raph L, H., Weezenbeek, ., Van Weezenbeek, K., et al.. - In: THE LANCET MICROBE. - ISSN 2666-5247. - (2024), pp. 1-14. [10.1016/S2666-5247(24)00134-4]