: Right heart failure (RHF) following implantation of a left ventricular assist device (LVAD) is a common and potentially serious condition with a wide spectrum of clinical presentations with an unfavourable effect on patient outcomes. Clinical scores that predict the occurrence of right ventricular (RV) failure have included multiple clinical, biochemical, imaging and haemodynamic parameters. However, unless the right ventricle is overtly dysfunctional with end-organ involvement, prediction of RHF post-LVAD implantation is, in most cases, difficult and inaccurate. For these reasons optimization of RV function in every patient is a reasonable practice aiming at preparing the right ventricle for a new and challenging haemodynamic environment after LVAD implantation. To this end, the institution of diuretics, inotropes and even temporary mechanical circulatory support may improve RV function, thereby preparing it for a better adaptation post-LVAD implantation. Furthermore, meticulous management of patients during the perioperative and immediate postoperative period should facilitate identification of RV failure refractory to medication. When RHF occurs late during chronic LVAD support, this is associated with worse long-term outcomes. Careful monitoring of RV function and characterization of the origination deficit should therefore continue throughout the patient's entire follow-up. Despite the useful information provided by the echocardiogram with respect to RV function, right heart catheterization frequently offers additional support for the assessment and optimization of RV function in LVAD-supported patients. In any patient candidate for LVAD therapy, evaluation and treatment of RV function and failure should be assessed in a multidimensional and multidisciplinary manner.

Right heart failure with left ventricular assist devices: Preoperative, perioperative and postoperative management strategies. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC / Adamopoulos, Stamatis; Bonios, Michael; Ben Gal, Tuvia; Gustafsson, Finn; Abdelhamid, Magdy; Adamo, Marianna; Bayes-Genis, Antonio; Böhm, Michael; Chioncel, Ovidiu; Cohen-Solal, Alain; Damman, Kevin; Di Nora, Concetta; Hashmani, Shahrukh; Hill, Loreena; Jaarsma, Tiny; Jankowska, Ewa; Lopatin, Yury; Masetti, Marco; Mehra, Mandeep R; Milicic, Davor; Moura, Brenda; Mullens, Wilfried; Nalbantgil, Sanem; Panagiotou, Chrysoula; Piepoli, Massimo; Rakisheva, Amina; Ristic, Arsen; Rivinius, Rasmus; Savarese, Gianluigi; Thum, Thomas; Tocchetti, Carlo Gabriele; Tops, Laurens F; Van Laake, Linda W; Volterrani, Maurizio; Seferovic, Petar; Coats, Andrew; Metra, Marco; Rosano, Giuseppe. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - (2024). [10.1002/ejhf.3323]

Right heart failure with left ventricular assist devices: Preoperative, perioperative and postoperative management strategies. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC

Piepoli, Massimo;Savarese, Gianluigi;Tocchetti, Carlo Gabriele;Rosano, Giuseppe
2024

Abstract

: Right heart failure (RHF) following implantation of a left ventricular assist device (LVAD) is a common and potentially serious condition with a wide spectrum of clinical presentations with an unfavourable effect on patient outcomes. Clinical scores that predict the occurrence of right ventricular (RV) failure have included multiple clinical, biochemical, imaging and haemodynamic parameters. However, unless the right ventricle is overtly dysfunctional with end-organ involvement, prediction of RHF post-LVAD implantation is, in most cases, difficult and inaccurate. For these reasons optimization of RV function in every patient is a reasonable practice aiming at preparing the right ventricle for a new and challenging haemodynamic environment after LVAD implantation. To this end, the institution of diuretics, inotropes and even temporary mechanical circulatory support may improve RV function, thereby preparing it for a better adaptation post-LVAD implantation. Furthermore, meticulous management of patients during the perioperative and immediate postoperative period should facilitate identification of RV failure refractory to medication. When RHF occurs late during chronic LVAD support, this is associated with worse long-term outcomes. Careful monitoring of RV function and characterization of the origination deficit should therefore continue throughout the patient's entire follow-up. Despite the useful information provided by the echocardiogram with respect to RV function, right heart catheterization frequently offers additional support for the assessment and optimization of RV function in LVAD-supported patients. In any patient candidate for LVAD therapy, evaluation and treatment of RV function and failure should be assessed in a multidimensional and multidisciplinary manner.
2024
Right heart failure with left ventricular assist devices: Preoperative, perioperative and postoperative management strategies. A clinical consensus statement of the Heart Failure Association (HFA) of the ESC / Adamopoulos, Stamatis; Bonios, Michael; Ben Gal, Tuvia; Gustafsson, Finn; Abdelhamid, Magdy; Adamo, Marianna; Bayes-Genis, Antonio; Böhm, Michael; Chioncel, Ovidiu; Cohen-Solal, Alain; Damman, Kevin; Di Nora, Concetta; Hashmani, Shahrukh; Hill, Loreena; Jaarsma, Tiny; Jankowska, Ewa; Lopatin, Yury; Masetti, Marco; Mehra, Mandeep R; Milicic, Davor; Moura, Brenda; Mullens, Wilfried; Nalbantgil, Sanem; Panagiotou, Chrysoula; Piepoli, Massimo; Rakisheva, Amina; Ristic, Arsen; Rivinius, Rasmus; Savarese, Gianluigi; Thum, Thomas; Tocchetti, Carlo Gabriele; Tops, Laurens F; Van Laake, Linda W; Volterrani, Maurizio; Seferovic, Petar; Coats, Andrew; Metra, Marco; Rosano, Giuseppe. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - (2024). [10.1002/ejhf.3323]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/962537
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