INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%–2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.

Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis / Tursi, A.; Piovani, D.; Brandimarte, G.; Di Mario, F.; Elisei, W.; Picchio, M.; Allegretta, L.; Annunziata, M. L.; Bafutto, M.; Bassotti, G.; Bianco, M. A.; Colucci, R.; Conigliaro, R.; Dumitrascu, D. L.; Escalante, R.; Ferrini, L.; Forti, G.; Franceschi, M.; Graziani, M. G.; Lammert, F.; Latella, G.; Maconi, G.; Compare, D.; Nardone, G.; de Castro Oliveira, L. C.; Oliveira, E. C.; Papagrigoriadis, S.; Pietrzak, A.; Pontone, S.; Stundiene, I.; Pranzo, G.; Reichert, M. C.; Rodino, S.; Regula, J.; Scaccianoce, G.; Scaldaferri, F.; Vassallo, R.; Zampaletta, C.; Zullo, A.; Spaziani, E.; Bonovas, S.; Papa, A.; Danese, S.. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 118:11(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]

Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis

Picchio M.;Annunziata M. L.;Forti G.;Compare D.;Nardone G.;Vassallo R.;Spaziani E.;
2023

Abstract

INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%–2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
2023
Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis / Tursi, A.; Piovani, D.; Brandimarte, G.; Di Mario, F.; Elisei, W.; Picchio, M.; Allegretta, L.; Annunziata, M. L.; Bafutto, M.; Bassotti, G.; Bianco, M. A.; Colucci, R.; Conigliaro, R.; Dumitrascu, D. L.; Escalante, R.; Ferrini, L.; Forti, G.; Franceschi, M.; Graziani, M. G.; Lammert, F.; Latella, G.; Maconi, G.; Compare, D.; Nardone, G.; de Castro Oliveira, L. C.; Oliveira, E. C.; Papagrigoriadis, S.; Pietrzak, A.; Pontone, S.; Stundiene, I.; Pranzo, G.; Reichert, M. C.; Rodino, S.; Regula, J.; Scaccianoce, G.; Scaldaferri, F.; Vassallo, R.; Zampaletta, C.; Zullo, A.; Spaziani, E.; Bonovas, S.; Papa, A.; Danese, S.. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 118:11(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/957644
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