INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%–2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.

Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis / Tursi, A., Piovani, D., Brandimarte, G., Di Mario, F., Elisei, W., Picchio, M., Allegretta, L., Annunziata, M.L., Bafutto, M., Bassotti, G., Bianco, M.A., Colucci, R., Conigliaro, R., Dumitrascu, D.L., Escalante, R., Ferrini, L., Forti, G., Franceschi, M., Graziani, M.G., Lammert, F., et al.. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 118:11(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]

Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis

Picchio M.;Annunziata M. L.;Forti G.;Compare D.;Nardone G.;Vassallo R.;Spaziani E.;
2023

Abstract

INTRODUCTION: We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis. METHODS: A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients. RESULTS: SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%–2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission. DISCUSSION: Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
2023
Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis / Tursi, A., Piovani, D., Brandimarte, G., Di Mario, F., Elisei, W., Picchio, M., Allegretta, L., Annunziata, M.L., Bafutto, M., Bassotti, G., Bianco, M.A., Colucci, R., Conigliaro, R., Dumitrascu, D.L., Escalante, R., Ferrini, L., Forti, G., Franceschi, M., Graziani, M.G., Lammert, F., et al.. - In: THE AMERICAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0002-9270. - 118:11(2023), pp. 2088-2092. [10.14309/ajg.0000000000002362]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/957644
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