Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level.
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor / Margarucci, Luigi; Monti, Maria Chiara; Cassiano, Chiara; Matteo, Mozzicafreddo; Mauro, Angeletti; Riccio, Raffaele; Tosco, Alessandra; Casapullo, Agostino. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 49:(2013), pp. 5844-5846. [10.1039/c3cc41858h]
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor
MONTI, Maria Chiara;CASSIANO, CHIARA;RICCIO, Raffaele;TOSCO, ALESSANDRA;CASAPULLO, Agostino
2013
Abstract
Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
chemcom_olc_2013.pdf
non disponibili
Licenza:
Non specificato
Dimensione
1.25 MB
Formato
Adobe PDF
|
1.25 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
