: The clinical implementation of liquid biopsy has dramatically modified the analytical paradigm for several solid tumors. To date, however, only circulating free DNA (cfDNA) has been approved in clinical practice to select targeted treatments for patients with colorectal cancer (CRC), non-small cell lung cancer (NSCLC), and breast cancer (BC). Interestingly, emerging liquid biopsy analytes in peripheral blood, including circulating tumor cells (CTC), miRNA, and extracellular vesicles (EVs), have been shown to play a crucial role in the clinical management of solid tumor patients. Here, we review how these blood-based biomarkers may positively impact early diagnosis, prognosis, and treatment response in ovarian cancer (OC) patients.

The role of liquid biopsy in epithelial ovarian cancer: state of the art / Della Corte, Luigi; Russo, Gianluca; Pepe, Francesco; Pisapia, Pasquale; Dell'Aquila, Michela; Malapelle, Umberto; Troncone, Giancarlo; Bifulco, Giuseppe; Giampaolino, Pierluigi. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - (2024), p. 104263. [10.1016/j.critrevonc.2024.104263]

The role of liquid biopsy in epithelial ovarian cancer: state of the art

Della Corte, Luigi;Russo, Gianluca;Pepe, Francesco;Pisapia, Pasquale;Dell'Aquila, Michela;Malapelle, Umberto;Troncone, Giancarlo;Bifulco, Giuseppe;Giampaolino, Pierluigi
2024

Abstract

: The clinical implementation of liquid biopsy has dramatically modified the analytical paradigm for several solid tumors. To date, however, only circulating free DNA (cfDNA) has been approved in clinical practice to select targeted treatments for patients with colorectal cancer (CRC), non-small cell lung cancer (NSCLC), and breast cancer (BC). Interestingly, emerging liquid biopsy analytes in peripheral blood, including circulating tumor cells (CTC), miRNA, and extracellular vesicles (EVs), have been shown to play a crucial role in the clinical management of solid tumor patients. Here, we review how these blood-based biomarkers may positively impact early diagnosis, prognosis, and treatment response in ovarian cancer (OC) patients.
2024
The role of liquid biopsy in epithelial ovarian cancer: state of the art / Della Corte, Luigi; Russo, Gianluca; Pepe, Francesco; Pisapia, Pasquale; Dell'Aquila, Michela; Malapelle, Umberto; Troncone, Giancarlo; Bifulco, Giuseppe; Giampaolino, Pierluigi. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - (2024), p. 104263. [10.1016/j.critrevonc.2024.104263]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/951122
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