: Archaea are microorganisms that comprise a distinct branch of the universal tree of life and which are best known as extremophiles, residing in a variety of environments characterized by harsh physical conditions. One seemingly universal trait of Archaea is the ability to perform N-glycosylation. At the same time, archaeal N-linked glycans present variety in terms of both composition and architecture not seen in the parallel eukaryal or bacterial processes. In this mini-review, many of the unique and unusual sugars found in archaeal N-linked glycans as identified by nuclear magnetic resonance spectroscopy are described.
N-glycosylation in Archaea: Unusual sugars and unique modifications / Notaro, Anna; Zaretsky, Marianna; Molinaro, Antonio; De Castro, Cristina; Eichler, Jerry. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - 534:(2023), p. 108963. [10.1016/j.carres.2023.108963]
N-glycosylation in Archaea: Unusual sugars and unique modifications
Molinaro, AntonioWriting – Review & Editing
;
2023
Abstract
: Archaea are microorganisms that comprise a distinct branch of the universal tree of life and which are best known as extremophiles, residing in a variety of environments characterized by harsh physical conditions. One seemingly universal trait of Archaea is the ability to perform N-glycosylation. At the same time, archaeal N-linked glycans present variety in terms of both composition and architecture not seen in the parallel eukaryal or bacterial processes. In this mini-review, many of the unique and unusual sugars found in archaeal N-linked glycans as identified by nuclear magnetic resonance spectroscopy are described.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.