Ischemic heart disease is the leading cause of mortality worldwide. In this context, myocar- dial viability is defined as the amount of myocardium that, despite contractile dysfunction, maintains metabolic and electrical function, having the potential for functional enhancement upon revascular- ization. Recent advances have improved methods to detect myocardial viability. The current paper summarizes the pathophysiological basis of the current methods used to detect myocardial viability in light of the advancements in the development of new radiotracers for cardiac imaging.
Tracers for Cardiac Imaging: Targeting the Future of Viable Myocardium / Nappi, Carmela; Panico, Mariarosaria; Falzarano, Maria; Vallone, Carlo; Ponsiglione, Andrea; Cutillo, Paolo; Zampella, Emilia; Petretta, Mario; Cuocolo, Alberto. - In: PHARMACEUTICS. - ISSN 1999-4923. - 15:5(2023), p. 1532. [10.3390/pharmaceutics15051532]
Tracers for Cardiac Imaging: Targeting the Future of Viable Myocardium
Nappi, Carmela
;Falzarano, Maria;Vallone, Carlo;Ponsiglione, Andrea;Cutillo, Paolo;Zampella, Emilia;Cuocolo, Alberto
2023
Abstract
Ischemic heart disease is the leading cause of mortality worldwide. In this context, myocar- dial viability is defined as the amount of myocardium that, despite contractile dysfunction, maintains metabolic and electrical function, having the potential for functional enhancement upon revascular- ization. Recent advances have improved methods to detect myocardial viability. The current paper summarizes the pathophysiological basis of the current methods used to detect myocardial viability in light of the advancements in the development of new radiotracers for cardiac imaging.File | Dimensione | Formato | |
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