: The secondary metabolites of plant origin belong to different and numerous classes of organic compounds. One of these is that of dimeric phenanthrenes, symmetrical or not, characterized by a series of interesting biological activities. Of these compounds, 37 have been isolated since 1988, from only five plant families. Considering each dimer comprises two phenanthrenes and starting from the hypothesis that each dimer is obtained through a biosynthetic mechanism that involves the coupling of the corresponding radicals of the individual phenanthrene units, it is possible to identify 29 phenanthrenes, of which 6 not yet isolated. It is possible to establish that 16 known phenanthrenes can be isolated from 14 different plant species, just as 6 new phenanthrenes can be isolated from 6 different plant species. This would allow a targeted analysis of a few natural extracts from specific plant sources to identify known or new molecules, with potential and/or specific biological activities.
Known or Never before Identified Phenanthrenes: Where It Is Possible to Isolate Them and Why / Di Fabio, Giovanni; Zarrelli, Armando. - In: CHEMISTRY & BIODIVERSITY. - ISSN 1612-1880. - 19:4(2022), p. e202100908. [10.1002/cbdv.202100908]
Known or Never before Identified Phenanthrenes: Where It Is Possible to Isolate Them and Why
Di Fabio, Giovanni;Zarrelli, Armando
2022
Abstract
: The secondary metabolites of plant origin belong to different and numerous classes of organic compounds. One of these is that of dimeric phenanthrenes, symmetrical or not, characterized by a series of interesting biological activities. Of these compounds, 37 have been isolated since 1988, from only five plant families. Considering each dimer comprises two phenanthrenes and starting from the hypothesis that each dimer is obtained through a biosynthetic mechanism that involves the coupling of the corresponding radicals of the individual phenanthrene units, it is possible to identify 29 phenanthrenes, of which 6 not yet isolated. It is possible to establish that 16 known phenanthrenes can be isolated from 14 different plant species, just as 6 new phenanthrenes can be isolated from 6 different plant species. This would allow a targeted analysis of a few natural extracts from specific plant sources to identify known or new molecules, with potential and/or specific biological activities.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.