: Self-assembling hydrogels are receiving great attention for both biomedical and technological applications. Self-assembly of protein/peptides as well as organic molecules is commonly induced in response to external triggers such as changes of temperature, concentration, or pH. An interesting strategy to modulate the morphology and mechanical properties of the gels implies the use of metal ions, where coordination bonds regulate the dynamic cross-linking in the construction of hydrogels, and coordination geometries, catalytic, and redox properties of metal ions play crucial roles. This review aims to discuss recent insights into the supramolecular assembly of hydrogels involving metal ions, with a focus on self-assembling peptides, as well as applications of metallogels in biomedical fields including tissue engineering, sensing, wound healing, and drug delivery.

Modulation of hydrogel networks by metal ions / La Manna, Sara; Florio, Daniele; Di Natale, Concetta; Marasco, Daniela. - In: JOURNAL OF PEPTIDE SCIENCE. - ISSN 1099-1387. - (2022). [10.1002/psc.3474]

Modulation of hydrogel networks by metal ions

La Manna, Sara;Florio, Daniele;Di Natale, Concetta;Marasco, Daniela
2022

Abstract

: Self-assembling hydrogels are receiving great attention for both biomedical and technological applications. Self-assembly of protein/peptides as well as organic molecules is commonly induced in response to external triggers such as changes of temperature, concentration, or pH. An interesting strategy to modulate the morphology and mechanical properties of the gels implies the use of metal ions, where coordination bonds regulate the dynamic cross-linking in the construction of hydrogels, and coordination geometries, catalytic, and redox properties of metal ions play crucial roles. This review aims to discuss recent insights into the supramolecular assembly of hydrogels involving metal ions, with a focus on self-assembling peptides, as well as applications of metallogels in biomedical fields including tissue engineering, sensing, wound healing, and drug delivery.
2022
Modulation of hydrogel networks by metal ions / La Manna, Sara; Florio, Daniele; Di Natale, Concetta; Marasco, Daniela. - In: JOURNAL OF PEPTIDE SCIENCE. - ISSN 1099-1387. - (2022). [10.1002/psc.3474]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/913137
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