The human primary sensory (S1) and primary motor (M1) hand areas feature high-frequency neuronal responses. Electrical nerve stimulation evokes high-frequency oscillations (HFO) at around 650 Hz in the contralateral S1. Likewise, transcranial magnetic stimulation (TMS) of M1 can evoke a series of descending volleys in the corticospinal pathway that can be detected non-invasively with a paired-pulse TMS protocol, called short interval intracortical facilitation (SICF). SICF features several peaks of facilitation of motor evoked potentials in contralateral hand muscles, which are separated by inter-peak intervals resembling HFO rhythmicity.
Relationship between high-frequency activity in the cortical sensory and the motor hand areas, and their myelin content / Tomasevic, Leo; Siebner, Hartwig Roman; Thielscher, Axel; Manganelli, Fiore; Pontillo, Giuseppe; Dubbioso, Raffaele. - In: BRAIN STIMULATION. - ISSN 1935-861X. - 15:3(2022), pp. 717-726. [10.1016/j.brs.2022.04.018]
Relationship between high-frequency activity in the cortical sensory and the motor hand areas, and their myelin content
Manganelli, Fiore;Pontillo, Giuseppe;Dubbioso, Raffaele
2022
Abstract
The human primary sensory (S1) and primary motor (M1) hand areas feature high-frequency neuronal responses. Electrical nerve stimulation evokes high-frequency oscillations (HFO) at around 650 Hz in the contralateral S1. Likewise, transcranial magnetic stimulation (TMS) of M1 can evoke a series of descending volleys in the corticospinal pathway that can be detected non-invasively with a paired-pulse TMS protocol, called short interval intracortical facilitation (SICF). SICF features several peaks of facilitation of motor evoked potentials in contralateral hand muscles, which are separated by inter-peak intervals resembling HFO rhythmicity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
