Because of its main role, increasing macromolecules transport in the interstitial region via advection is of primary task in fields like drug delivery. These phenomena can be investigated by means of a two-phase thermoporoelastic model, where it has been shown that temperature gradient would have a role in this. In this study, a 1D spherical tumor tissue under a constant heat source is investigated to see how induced temperature gradients affect interstitial fluid pressure and velocity. From the results, it is shown that these applied temperatures would help the flow distribution by varying pressure and velocity through the domain.
A Thermoporoelastic Model For Interstitial Fluid Transport With A Constant Heat Source / Andreozzi, Assunta; Iasiello, Marcello; Netti, PAOLO ANTONIO. - (2022).
A Thermoporoelastic Model For Interstitial Fluid Transport With A Constant Heat Source
Assunta Andreozzi;Marcello Iasiello
;Paolo Antonio Netti
2022
Abstract
Because of its main role, increasing macromolecules transport in the interstitial region via advection is of primary task in fields like drug delivery. These phenomena can be investigated by means of a two-phase thermoporoelastic model, where it has been shown that temperature gradient would have a role in this. In this study, a 1D spherical tumor tissue under a constant heat source is investigated to see how induced temperature gradients affect interstitial fluid pressure and velocity. From the results, it is shown that these applied temperatures would help the flow distribution by varying pressure and velocity through the domain.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.