Because of its main role, increasing macromolecules transport in the interstitial region via advection is of primary task in fields like drug delivery. These phenomena can be investigated by means of a two-phase thermoporoelastic model, where it has been shown that temperature gradient would have a role in this. In this study, a 1D spherical tumor tissue under a constant heat source is investigated to see how induced temperature gradients affect interstitial fluid pressure and velocity. From the results, it is shown that these applied temperatures would help the flow distribution by varying pressure and velocity through the domain.

A Thermoporoelastic Model For Interstitial Fluid Transport With A Constant Heat Source

Assunta Andreozzi;Marcello Iasiello
;
Paolo Antonio Netti
2022

Abstract

Because of its main role, increasing macromolecules transport in the interstitial region via advection is of primary task in fields like drug delivery. These phenomena can be investigated by means of a two-phase thermoporoelastic model, where it has been shown that temperature gradient would have a role in this. In this study, a 1D spherical tumor tissue under a constant heat source is investigated to see how induced temperature gradients affect interstitial fluid pressure and velocity. From the results, it is shown that these applied temperatures would help the flow distribution by varying pressure and velocity through the domain.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/897303
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