Coronavirus disease 2019 (COVID-19) has quickly become a global pandemic. Reports from different parts of the world indicate that a significant proportion of people who have recovered from COVID-19 are suffering from various health problems collectively referred to as "long COVID-19". Common symptoms include fatigue, shortness of breath, cough, joint pain, chest pain, muscle aches, headaches, and so on. Vitamin D is an immunomodulatory hormone with proven efficacy against various upper respiratory tract infections. Vitamin D can inhibit hyperinflammatory reactions and accelerate the healing process in the affected areas, especially in lung tissue. Moreover, vitamin D deficiency has been associated with the severity and mortality of COVID-19 cases, with a high prevalence of hypovitaminosis D found in patients with COVID-19 and acute respiratory failure. Thus, there are promising reasons to promote research into the effects of vitamin D supplementation in COVID-19 patients. However, no studies to date have found that vitamin D affects post-COVID-19 symptoms or biomarkers. Based on this scenario, this review aims to provide an up-to-date overview of the potential role of vitamin D in long COVID-19 and of the current literature on this topic.

Vitamin D: A Role Also in Long COVID-19? / Barrea, Luigi; Verde, Ludovica; Grant, William B; Frias-Toral, Evelyn; Sarno, Gerardo; Vetrani, Claudia; Ceriani, Florencia; Garcia-Velasquez, Eloisa; Contreras-Briceño, José; Savastano, Silvia; Colao, Annamaria; Muscogiuri, Giovanna. - In: NUTRIENTS. - ISSN 2072-6643. - 14:8(2022), p. 1625. [10.3390/nu14081625]

Vitamin D: A Role Also in Long COVID-19?

Barrea, Luigi;Verde, Ludovica;Vetrani, Claudia;Savastano, Silvia;Colao, Annamaria;Muscogiuri, Giovanna
Ultimo
2022

Abstract

Coronavirus disease 2019 (COVID-19) has quickly become a global pandemic. Reports from different parts of the world indicate that a significant proportion of people who have recovered from COVID-19 are suffering from various health problems collectively referred to as "long COVID-19". Common symptoms include fatigue, shortness of breath, cough, joint pain, chest pain, muscle aches, headaches, and so on. Vitamin D is an immunomodulatory hormone with proven efficacy against various upper respiratory tract infections. Vitamin D can inhibit hyperinflammatory reactions and accelerate the healing process in the affected areas, especially in lung tissue. Moreover, vitamin D deficiency has been associated with the severity and mortality of COVID-19 cases, with a high prevalence of hypovitaminosis D found in patients with COVID-19 and acute respiratory failure. Thus, there are promising reasons to promote research into the effects of vitamin D supplementation in COVID-19 patients. However, no studies to date have found that vitamin D affects post-COVID-19 symptoms or biomarkers. Based on this scenario, this review aims to provide an up-to-date overview of the potential role of vitamin D in long COVID-19 and of the current literature on this topic.
2022
Vitamin D: A Role Also in Long COVID-19? / Barrea, Luigi; Verde, Ludovica; Grant, William B; Frias-Toral, Evelyn; Sarno, Gerardo; Vetrani, Claudia; Ceriani, Florencia; Garcia-Velasquez, Eloisa; Contreras-Briceño, José; Savastano, Silvia; Colao, Annamaria; Muscogiuri, Giovanna. - In: NUTRIENTS. - ISSN 2072-6643. - 14:8(2022), p. 1625. [10.3390/nu14081625]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/894277
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