Early pathogenesis of diabetic cardiomyopathy (DMCM) may involve lipotoxicity of cardiomyocytes in the context of hyperglycemia. There are many preclinical studies of DMCM pathogenesis, but the human evidence is still poorly understood.
Lipid Accumulation in Hearts Transplanted From Nondiabetic Donors to Diabetic Recipients / Marfella, Raffaele; Amarelli, Cristiano; Cacciatore, Francesco; Balestrieri, Maria Luisa; Mansueto, Gelsomina; D'Onofrio, Nunzia; Esposito, Salvatore; Mattucci, Irene; Salerno, Gemma; De Feo, Marisa; D'Amico, Michele; Golino, Paolo; Maiello, Ciro; Paolisso, Giuseppe; Napoli, Claudio. - In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. - ISSN 1558-3597. - 75:11(2020), pp. 1249-1262. [10.1016/j.jacc.2020.01.018]
Lipid Accumulation in Hearts Transplanted From Nondiabetic Donors to Diabetic Recipients
Cacciatore, Francesco;Maiello, Ciro;
2020
Abstract
Early pathogenesis of diabetic cardiomyopathy (DMCM) may involve lipotoxicity of cardiomyocytes in the context of hyperglycemia. There are many preclinical studies of DMCM pathogenesis, but the human evidence is still poorly understood.| File | Dimensione | Formato | |
|---|---|---|---|
|
MArfella R et al. JACC 2020.pdf
solo utenti autorizzati
Tipologia:
Versione Editoriale (PDF)
Licenza:
Accesso privato/ristretto
Dimensione
1.7 MB
Formato
Adobe PDF
|
1.7 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
