We reported on five people with MS, using immunodepleting disease modifying treatments (anti-CD20 monoclonal antibodies and sphingosine-one-phosphate modulators) and with reduced COVID-19 vaccine response, who had mild-to-moderate symptomatic COVID-19, and were treated with anti-SARS-CoV-2 monoclonal antibodies. In particular, we showed the possibility to use monoclonal antibodies to speed-up recovery from COVID-19 in MS, in the absence of any COVID-19 residuals or MS changes (e.g., relapses or disability).

Monoclonal antibodies for mild-to-moderate COVID-19 in multiple sclerosis: A case series

Moccia, Marcello;Buonomo, Antonio Riccardo;Scotto, Riccardo;Viceconte, Giulio;Nobile, Mariano;Lanzillo, Roberta;Brescia Morra, Vincenzo;Gentile, Ivan
2022

Abstract

We reported on five people with MS, using immunodepleting disease modifying treatments (anti-CD20 monoclonal antibodies and sphingosine-one-phosphate modulators) and with reduced COVID-19 vaccine response, who had mild-to-moderate symptomatic COVID-19, and were treated with anti-SARS-CoV-2 monoclonal antibodies. In particular, we showed the possibility to use monoclonal antibodies to speed-up recovery from COVID-19 in MS, in the absence of any COVID-19 residuals or MS changes (e.g., relapses or disability).
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/891486
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