Some biologics for psoriasis, especially anti-tumor necrosis factor (TNF)-α therapies, may re-activate latent tuberculosis (TBC) infection with consequent morbidity and mortality. However, there is a low reported incidence of conversion to positive TBC status among patients with psoriasis treated with second-generation biologic therapies, particularly anti-interleukin (IL)-17 therapies such as secukinumab.

Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection / Megna, Matteo; Patruno, Cataldo; Rita Bongiorno, Maria; Gambardella, Alessio; Guarneri, Claudio; Foti, Caterina; Lembo, Serena; Loconsole, Francesco; Fabbrocini, Gabriella. - In: JOURNAL OF DERMATOLOGICAL TREATMENT. - ISSN 1471-1753. - (2022), pp. 1-5. [10.1080/09546634.2022.2062280]

Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection

Matteo Megna
;
Cataldo Patruno;Alessio Gambardella;Serena Lembo;Gabriella Fabbrocini
2022

Abstract

Some biologics for psoriasis, especially anti-tumor necrosis factor (TNF)-α therapies, may re-activate latent tuberculosis (TBC) infection with consequent morbidity and mortality. However, there is a low reported incidence of conversion to positive TBC status among patients with psoriasis treated with second-generation biologic therapies, particularly anti-interleukin (IL)-17 therapies such as secukinumab.
2022
Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection / Megna, Matteo; Patruno, Cataldo; Rita Bongiorno, Maria; Gambardella, Alessio; Guarneri, Claudio; Foti, Caterina; Lembo, Serena; Loconsole, Francesco; Fabbrocini, Gabriella. - In: JOURNAL OF DERMATOLOGICAL TREATMENT. - ISSN 1471-1753. - (2022), pp. 1-5. [10.1080/09546634.2022.2062280]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/890861
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