Poly (ADP-ribose) polymerase-inhibitors (PARPis) showed antitumour activity in BRCA1/2-mutated cancers, with more heterogeneous outcomes in tumours harbouring mutations that impair other genes involved in the DNA homologous recombination repair (HRR) or wild-type (wt).

Poly (ADP-ribose) polymerase inhibitors in solid tumours: Systematic review and meta-analysis

Schettini, Francesco;Giuliano, Mario;Locci, Mariavittoria;De Placido, Sabino;
2021

Abstract

Poly (ADP-ribose) polymerase-inhibitors (PARPis) showed antitumour activity in BRCA1/2-mutated cancers, with more heterogeneous outcomes in tumours harbouring mutations that impair other genes involved in the DNA homologous recombination repair (HRR) or wild-type (wt).
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11588/890578
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