Management and control of the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus SARS-CoV-2 is critically dependent on quick and reliable identification of the virus in clinical specimens. Detection of viral RNA by a colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a simple, reliable and cost-effective assay, deployable in resource-limited settings (RLS). Our objective was to evaluate the intrinsic and extrinsic performances of RT-LAMP in RLS.
Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan Africa / Baba, M.M., Bitew, M., Fokam, J., Lelo, E.A., Ahidjo, A., Asmamaw, K., Beloumou, G.A., Bulimo, W.D., Buratti, E., Chenwi, C., Dadi, H., D'Agaro, P., De Conti, L., Fainguem, N., Gadzama, G., Maiuri, P., Majanja, J., Meshack, W., Ndjolo, A., Nkenfou, C., et al.. - In: ECLINICALMEDICINE. - ISSN 2589-5370. - 40:(2021). [10.1016/j.eclinm.2021.101101]
Diagnostic performance of a colorimetric RT -LAMP for the identification of SARS-CoV-2: A multicenter prospective clinical evaluation in sub-Saharan Africa
Maiuri, Paolo;
2021
Abstract
Management and control of the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus SARS-CoV-2 is critically dependent on quick and reliable identification of the virus in clinical specimens. Detection of viral RNA by a colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) is a simple, reliable and cost-effective assay, deployable in resource-limited settings (RLS). Our objective was to evaluate the intrinsic and extrinsic performances of RT-LAMP in RLS.| File | Dimensione | Formato | |
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