Marine diatoms produce r,â,ç,ä-unsaturated aldehydes that have detrimental effects on the reproduction of their natural predators. The production of these defensive metabolites is suggested to involve enzymatic oxidation of polyunsaturated fatty acids. In this paper, feeding experiments with labeled precursor provide clear evidence in support of the origin of octadienals 1 and 2 from 6,9,12-hexadecatrienoic acid (5), thus proving the involvement of novel lipoxygenase/lyase activity for the oxidation of C16 fatty acids.
Production of octadienal in the marine diatom Skeletonema costatum / D’Ippolito, G.; Romano, G.; Caruso, T.; Spinella, A.; Cimino, G.; Fontana, A. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 5:6(2003), pp. 885-887. [10.1021/ol034057c]
Production of octadienal in the marine diatom Skeletonema costatum
Fontana A
2003
Abstract
Marine diatoms produce r,â,ç,ä-unsaturated aldehydes that have detrimental effects on the reproduction of their natural predators. The production of these defensive metabolites is suggested to involve enzymatic oxidation of polyunsaturated fatty acids. In this paper, feeding experiments with labeled precursor provide clear evidence in support of the origin of octadienals 1 and 2 from 6,9,12-hexadecatrienoic acid (5), thus proving the involvement of novel lipoxygenase/lyase activity for the oxidation of C16 fatty acids.| File | Dimensione | Formato | |
|---|---|---|---|
|
2003 Org Lett_ Biosynthesis C8 PUAs.pdf
non disponibili
Dimensione
66.67 kB
Formato
Adobe PDF
|
66.67 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
