From the Antarctic sponge Lyssodendoryx flabellata, a new polycyclic compound, which we named flabellone, related to the oestrogenic hormone oestrone, has been elucidated by spectrometric and spectroscopic means. Along with flabellone, a glycosphingolipid (GSL) mixture featuring an unusual -fucofuranosyl-3--glucopyranoside unit structurally identical to the previously reported terpioside has been isolated and identified. The mixture of GSL homologues exhibited inhibitory effects in mixed lymphocyte reactions on human cells.
A chemical investigation of the Antarctic sponge Lyssodendoryx flabellata / A., Cutignano; R., De Palma; Fontana, A. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6419. - 13:(2012), pp. 1240-1248. [0.1080/14786419.2011.561493]
A chemical investigation of the Antarctic sponge Lyssodendoryx flabellata
Fontana A
2012
Abstract
From the Antarctic sponge Lyssodendoryx flabellata, a new polycyclic compound, which we named flabellone, related to the oestrogenic hormone oestrone, has been elucidated by spectrometric and spectroscopic means. Along with flabellone, a glycosphingolipid (GSL) mixture featuring an unusual -fucofuranosyl-3--glucopyranoside unit structurally identical to the previously reported terpioside has been isolated and identified. The mixture of GSL homologues exhibited inhibitory effects in mixed lymphocyte reactions on human cells.| File | Dimensione | Formato | |
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