Introduction Foodborne botulism is a neuroparalytic disease caused by ingestion of food contaminated with botulinum toxins. Despite rare the mortality rate is high if untreated. Diagnosis of botulism is still a challenge for clinician, due to the variability of clinical manifestations and disease course. We report on a child with type B botulin intoxication who was early diagnosed and treated underlining that clinical suspicion is crucial to start prompt treatment. Case presentation An 11-year-old boy presented with bilateral ptosis and mydriasis, dry mouth, difficulty in swallowing, dysphonia, urine retention and constipation. Clear sensorium and no fever were observed. Immediately the suspicion of botulism was risen and botulinum antitoxin was administered. 3 days later serum and rectal samples tested positive for Clostridium botulinum. The patient completely recovered when discharged from hospital. Discussion Foodborne botulism is still possible in developed countries. The confirmation test of botulism requires some days. To avoid long delays between intoxication and diagnosis prompt clinical suspicion is thus crucial. The outcome depends on rapid implementation of appropriate management with intensive respiratory care and antitoxin administration.

Early diagnosis and treatment in a child with foodborne botulism / Proverbio, M. R.; Lamba, M.; Rossi, A.; Siani, P.. - In: ANAEROBE. - ISSN 1075-9964. - 39:(2016), pp. 189-192. [10.1016/j.anaerobe.2015.12.002]

Early diagnosis and treatment in a child with foodborne botulism

Rossi A.;
2016

Abstract

Introduction Foodborne botulism is a neuroparalytic disease caused by ingestion of food contaminated with botulinum toxins. Despite rare the mortality rate is high if untreated. Diagnosis of botulism is still a challenge for clinician, due to the variability of clinical manifestations and disease course. We report on a child with type B botulin intoxication who was early diagnosed and treated underlining that clinical suspicion is crucial to start prompt treatment. Case presentation An 11-year-old boy presented with bilateral ptosis and mydriasis, dry mouth, difficulty in swallowing, dysphonia, urine retention and constipation. Clear sensorium and no fever were observed. Immediately the suspicion of botulism was risen and botulinum antitoxin was administered. 3 days later serum and rectal samples tested positive for Clostridium botulinum. The patient completely recovered when discharged from hospital. Discussion Foodborne botulism is still possible in developed countries. The confirmation test of botulism requires some days. To avoid long delays between intoxication and diagnosis prompt clinical suspicion is thus crucial. The outcome depends on rapid implementation of appropriate management with intensive respiratory care and antitoxin administration.
2016
Early diagnosis and treatment in a child with foodborne botulism / Proverbio, M. R.; Lamba, M.; Rossi, A.; Siani, P.. - In: ANAEROBE. - ISSN 1075-9964. - 39:(2016), pp. 189-192. [10.1016/j.anaerobe.2015.12.002]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/876030
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