Primary diffuse leptomeningeal melanomatosis is a rare and very aggressive neoplasm with only 6 pediatric cases reported so far. Recognizing this condition is unfortunately difficult due to the nonspecific clinical presentation. Nevertheless, imaging may help in a timely diagnosis that can better direct the management of these patients, especially in the light of the rapidly ominous course of the pathology. We describe three cases of pediatric primary diffuse leptomeningeal melanomatosis and review the literature regarding this entity, focusing on computed tomography and magnetic resonance imaging findings.

Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature / Pezzullo, Giovanna; Ugga, Lorenzo; Cuocolo, Renato; Perillo, Teresa; D’Amico, Alessandra. - In: MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY. - ISSN 1865-5041. - (2021). [10.1007/s12254-021-00720-6]

Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature

Pezzullo, Giovanna
;
Ugga, Lorenzo;Cuocolo, Renato;Perillo, Teresa;
2021

Abstract

Primary diffuse leptomeningeal melanomatosis is a rare and very aggressive neoplasm with only 6 pediatric cases reported so far. Recognizing this condition is unfortunately difficult due to the nonspecific clinical presentation. Nevertheless, imaging may help in a timely diagnosis that can better direct the management of these patients, especially in the light of the rapidly ominous course of the pathology. We describe three cases of pediatric primary diffuse leptomeningeal melanomatosis and review the literature regarding this entity, focusing on computed tomography and magnetic resonance imaging findings.
2021
Primary diffuse leptomeningeal melanomatosis: report of three pediatric cases and review of the literature / Pezzullo, Giovanna; Ugga, Lorenzo; Cuocolo, Renato; Perillo, Teresa; D’Amico, Alessandra. - In: MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY. - ISSN 1865-5041. - (2021). [10.1007/s12254-021-00720-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/853756
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