Extracellular vesicles are important biomarkers and therapeutic targets for breast cancer (BC). However, specific tools for their recognition are lacking. Condorelli and colleagues describe the finding of a high-affinity aptamer (ex-50.T) able to specifically target BC exosomes acting as a promising diagnostic and therapeutic tool.
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes / Esposito, Carla Lucia; Quintavalle, Cristina; Ingenito, Francesco; Rotoli, Deborah; Roscigno, Giuseppina; Nuzzo, Silvia; Thomas, Renato; Catuogno, Silvia; de Franciscis, Vittorio; Condorelli, Gerolama. - In: MOLECULAR THERAPY NUCLEIC ACIDS. - ISSN 2162-2531. - 23:(2021), pp. 982-994. [10.1016/j.omtn.2021.01.012]
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes
Esposito, Carla Lucia;Quintavalle, Cristina;Ingenito, Francesco;Rotoli, Deborah;Roscigno, Giuseppina;Nuzzo, Silvia;Condorelli, Gerolama
2021
Abstract
Extracellular vesicles are important biomarkers and therapeutic targets for breast cancer (BC). However, specific tools for their recognition are lacking. Condorelli and colleagues describe the finding of a high-affinity aptamer (ex-50.T) able to specifically target BC exosomes acting as a promising diagnostic and therapeutic tool.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
